Results 121 to 130 of about 5,555,873 (373)

BV Yang-Mills as a Homotopy Chern-Simons via SFT

open access: yes, 2009
We show explicitly how BV Yang-Mills action emerges as a homotopy generalization of Chern-Simons theory from the algebraic constructions arising from String Field Theory.Comment: LaTeX2e, 22 pages, minor revisions, typos corrected, references added ...
Zeitlin, Anton M.
core   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

The Dynamical Emergence of Biology From Physics: Branching Causation via Biomolecules

open access: yesFrontiers in Physiology, 2019
Biology differs fundamentally from the physics that underlies it. This paper1 proposes that the essential difference is that while physics at its fundamental level is Hamiltonian, in biology, once life has come into existence, causation of a contextual ...
George F. R. Ellis, Jonathan Kopel
doaj   +1 more source

Extending Feynman's Formalisms for Modelling Human Joint Action Coordination

open access: yes, 2009
The recently developed Life-Space-Foam approach to goal-directed human action deals with individual actor dynamics. This paper applies the model to characterize the dynamics of co-action by two or more actors. This dynamics is modelled by: (i) a two-term
Bernstein N. A.   +9 more
core   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

PhyLab – a virtual reality laboratory for experiments in physics: a pilot study on intervention effectiveness and gender differences

open access: yesFrontiers in Psychology
IntroductionNew technologies have great potential to facilitate students’ understanding and appreciation of one of the most abstract and challenging school subjects – physics.
Selma Korlat   +6 more
doaj   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

DISCUSION ACERCA DE LA UTILIDAD E IMPORTANCIA DE LOS LABORATATORIOS DE FISICA EN LA ENSEÑANZA ACTUAL [PDF]

open access: yesGondola, 2010
n the process of teaching and learning of physics, are referenced various scenarios in which interaction takes place between actors involved in this process. One of the main sites is the laboratory, this has been vital throughout scientific history.
ARNULFO SEGURA, JEIMY LORENA PEREZ
doaj  

Spooky Action at a Temporal Distance

open access: yesEntropy, 2018
Since the discovery of Bell’s theorem, the physics community has come to take seriously the possibility that the universe might contain physical processes which are spatially nonlocal, but there has been no such revolution with regard to the possibility ...
Emily Adlam
semanticscholar   +1 more source

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