Results 91 to 100 of about 772,376 (319)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
The generation and conduction of action potentials represents a fundamental means of communication in the nervous system, and is a metabolically expensive process.
Liu, Liwei, Yu, Lianchun
core +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Recent Developments in Cardiac Contractility Modulation for Heart Failure [PDF]
None.
Joshua R. Hirsch, MD, Hamid Afshar, MD
doaj +1 more source
Investigation of otolith responses using ground based vestibular research facility [PDF]
The general goal was to examine tilt sensitivity of horizontal semicircular canal afferents. Computer programs were tested which controlled the short axis centrifuge at the Vestibular Research Facility, acquired action potentials and produced data ...
Correia, Manning J., TABARACCI
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Compactifications with S-Duality Twists
We consider generalised Scherk Schwarz reductions of supergravity and superstring theories with twists by electromagnetic dualities that are symmetries of the equations of motion but not of the action, such as the S-duality of D=4, N=4 super-Yang-Mills ...
A. Dabholkar +34 more
core +1 more source

