Results 91 to 100 of about 749,554 (288)
Research in Pharmaceutical SciencesBackground and purpose: Spinal cord injury (SCI) causes motor and cognitive impairments, with secondary hippocampal damage contributing to memory deficits.
Amirhossein Rabiei Rad +6 more
doaj +1 more source
Recent Developments in Cardiac Contractility Modulation for Heart Failure [PDF]
Texas Heart Institute JournalNone.
Joshua R. Hirsch, MD, Hamid Afshar, MD
doaj +1 more source
Post-inflationary phases stiffer than radiation and Palatini formulation
, 2019 If the inflaton and the quintessence fields are identified, the background geometry evolves through a stiff epoch undershooting the expansion rate of a radiation-dominated plasma.
Giovannini, Massimo
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2018 In the auditory system, tonotopy is the spatial arrangement of where sounds of different frequencies are processed. Defined by the organization of neurons and their inputs, tonotopy emphasizes distinctions in neuronal structure and function across ...
Hui Hong +10 more
doaj +1 more source
Investigation of otolith responses using ground based vestibular research facility [PDF]
The general goal was to examine tilt sensitivity of horizontal semicircular canal afferents. Computer programs were tested which controlled the short axis centrifuge at the Vestibular Research Facility, acquired action potentials and produced data ...
Correia, Manning J., TABARACCI
core +1 more source