Results 91 to 100 of about 3,738,124 (301)

A Spreadsheet Implementation of the Hodgkin- Huxley Model for Action Potentials in Neurons [PDF]

, 2017
A Microsoft Excel workbook is presented that enables students to explore the Hodgkin-Huxley Model for action potentials in neurons. The model is implemented by a system of four coupled nonlinear ordinary differential equations and requires a numerical ...
Florian Henning Geyer
core  

Na+ Action Potentials in Human Photoreceptors

, 2001
Mammalian photoreceptors are hyperpolarized by a light stimulus and are commonly thought to be nonspiking neurons. We used the whole-cell patch-clamp technique on surgically excised human retina to examine whether human photoreceptors can elicit action ...
Miyachi, Ei-ichi, Horiguchi, Masayuki, Suzuki, Hiromitsu, Kawai, Fusao   +3 more
core   +1 more source

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

Optimizing Optogenetic Activation of Purkinje Cell Axons to Investigate the Purkinje Cell – DCN Synapse

Frontiers in Synaptic Neuroscience, 2019
Optogenetics is a state-of-the-art tool for interrogating neural circuits. In the cerebellum, Purkinje cells serve as the sole output of the cerebellar cortex where they synapse on neurons in the deep cerebellar nuclei (DCN).
Kim M. Gruver, Kim M. Gruver, Alanna J. Watt   +2 more
doaj   +1 more source

Velocity recovery cycles of human muscle action potentials: Repeatability and variability

, 2011
Velocity recovery cycles (VRCs) of human muscle action potentials have been proposed as a new technique for assessing muscle membrane function in myopathies. This study was undertaken to determine the variability and repeatability of VRC measures such as
Troller, Rebekka, Humm, Andrea M, Werner J. Z’Graggen, Karin A. Ackermann, Z'graggen, Werner J, Andrea M. Humm, Ackermann, Karin A, Bostock, Hugh, Hugh Bostock, Rebekka Troller, Bostock H, Humm AM, Troller R, Z'graggen WJ, Ackermann KA   +14 more
core   +1 more source

Uncovering Inequities: The Role of Social Determinants of Health in Hospitalized Adolescents and Young Adults With Heavy Menstrual Bleeding

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres, Cristina Tarango, Ashley Childress, Chunyan Liu, Evan Thomas, Jennifer Pomales, Eric S. Mullins   +6 more
wiley   +1 more source

Analogue modulation of back-propagating action potentials enables dendritic hybrid signalling

Nature Communications, 2016
‘Analogue’ modulation by somatic membrane potentials can modify ‘digital’ axonal action potentials. Here, the authors show that analogue modulation can occur in back-propagating dendritic action potentials and calcium signals, leading to signal ...
János Brunner, János Szabadics
doaj   +1 more source

Action potential energy efficiency varies among neuron types in vertebrates and invertebrates [PDF]

, 2010
The initiation and propagation of action potentials (APs) places high demands on the energetic resources of neural tissue. Each AP forces ATP-driven ion pumps to work harder to restore the ionic concentration gradients, thus consuming more energy.
Biswa Sengupta, Simon B Laughlin (16038959), Martin Stemmler (246371), Sengupta, Biswa, Jeremy E Niven, Jeremy Niven (4463341), Stemmler, Martin B., Martin Stemmler, Simon B Laughlin, Niven, Jeremy E., Simon B. Laughlin, Laughlin, Simon B., Jeremy E. Niven, Biswa Sengupta (246370), Niven Jeremy E., Laughlin Simon B., Sengupta Biswa, Stemmler Martin   +17 more
core   +2 more sources

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Hippocampal synaptic markers and cognitive recovery in spinal cord injury: the therapeutic potential of neural stem cell-laden carbon nanotube-based fiber scaffolds with liposomal hesperidin

Research in Pharmaceutical Sciences
Background and purpose: Spinal cord injury (SCI) causes motor and cognitive impairments, with secondary hippocampal damage contributing to memory deficits.
Amirhossein Rabiei Rad, Tahere Mokhtari, Esmael Amirazodi, Amir Mahdi Molavi, Fatemeh Mortazavi Moghadam, Reza Kazemi Oskuee, Arman Abroumand Gholami   +6 more
doaj   +1 more source