Results 91 to 100 of about 4,325 (209)

Recording Intracellular Potentials of Viscerono-ciceptive Neurons in Posterior Group of Thalamic Nuclei(PO)and Their Labeling with HRP Intracelluiarly in Cats

针刺研究, 1993
Intracellular potentials(ICP)of the neurons in PO evoked by stimulating greater splanchnicnerve(GSN)were recorded in 42 cats.The resting potentials and action potentials induced by stimu-lating GSN were 53.74±11.68 mV and 29.44±9.22 mV respectively.Owing
Teng Guexi Meng Xianwei Liu Shuzheng Ma Xiaoling
doaj  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Polypyrrole Coatings as Possible Solutions for Sensing and Stimulation in Bioelectronic Medicines

Biosensors
Bioelectronic medicines record biological signals and provide electrical stimulation for the treatment of diseases. Advanced bioelectronic therapies require the development of electrodes that match the softness of the implanted tissues, as the present ...
Cristian Sevcencu, Izabella Crăciunescu, Alin-Alexandru Andrei, Maria Suciu, Sergiu Macavei, Lucian Barbu-Tudoran   +5 more
doaj   +1 more source

Integrating with Action Potentials [PDF]

Neuron, 2000
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Toward Subcellular Action Potential Detection with Nanodiamond Quantum Magnetometry

Nanomaterials
Quantum sensing with nitrogen vacancy (NV) defects in diamond enables detection of extremely small changes in temperature, host material strain, and magnetic and electric fields.
Azmath Fathima, Peker Milas, Sheikh Mahtab, Tanmay Talukder, Mya Merritt, James Wachira, Solomon Tadesse, Michael Spencer, Birol Ozturk   +8 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source