Results 241 to 250 of about 772,376 (319)

Modulatory Impact of Oxidative Stress on Action Potentials in Pathophysiological States: A Comprehensive Review. [PDF]

Antioxidants (Basel)
Mahapatra C, Thakkar R, Kumar R.
europepmc   +1 more source

Photolipid excitation triggers depolarizing optocapacitive currents and action potentials

, 2023
Bassetto CAZ, Pfeffermann J, Yadav R, Strassgschwandtner S, Glasnov T, Bezanilla F, Pohl P.   +6 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Influence of Cochlear Anatomy on Intraoperative Electrically Evoked Compound Action Potentials. [PDF]

J Clin Med
Fatani N, Abdelsamad Y, Alsanosi A.
europepmc   +1 more source

Status Report on Topical Hypochlorous Acid: Clinical Relevance of Specific Formulations, Potential Modes of Action, and Study Outcomes.

, 2018
J.Q. Del Rosso, Neal Bhatia
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Electrically evoked compound action potentials are associated with the site of intracochlear stimulation. [PDF]

Eur Arch Otorhinolaryngol
Weiss NM, Breitsprecher T, Völter C, Lammers M, Van de Heyning P, Dazert S, Van Rompaey V.   +6 more
europepmc   +1 more source

Estradiol-modified prolactin secretion independently of action potentials and Ca2+ and blockade of outward potassium currents in GH3 cells

, 2016
Manuel Sánchez, Lorena Suárez, Begoña Cantabrana, Javier Bordallo   +3 more
openalex   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Intelligent in-cell electrophysiology: Reconstructing intracellular action potentials using a physics-informed deep learning model trained on nanoelectrode array recordings. [PDF]

Nat Commun
Rahmani K, Yang Y, Foster EP, Tsai CT, Meganathan DP, Alvarez DD, Gupta A, Cui B, Santoro F, Bloodgood BL, Yu R, Forro C, Jahed Z.   +12 more
europepmc   +1 more source