Results 291 to 300 of about 14,230,890 (402)

Modulatory Impact of Oxidative Stress on Action Potentials in Pathophysiological States: A Comprehensive Review. [PDF]

Antioxidants (Basel)
Mahapatra C, Thakkar R, Kumar R.
europepmc   +1 more source

The periodic axon membrane skeleton leads to Na nanodomains but does not impact action potentials. [PDF]

Biophys J, 2022
Chai Z, Tzingounis AV, Lykotrafitis G.
europepmc   +1 more source

Linear Superposition of Retinal Action Potentials to Predict Electrical Flicker Responses from the Eye of the Wolf Spider, Lycosa baltimoriana (Keyserling) [PDF]

, 1962
Robert D. DeVoe
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Intelligent in-cell electrophysiology: Reconstructing intracellular action potentials using a physics-informed deep learning model trained on nanoelectrode array recordings. [PDF]

Nat Commun
Rahmani K, Yang Y, Foster EP, Tsai CT, Meganathan DP, Alvarez DD, Gupta A, Cui B, Santoro F, Bloodgood BL, Yu R, Forro C, Jahed Z.   +12 more
europepmc   +1 more source

Acute effects of cochleostomy and electrode-array insertion on compound action potentials in normal-hearing guinea pigs. [PDF]

Front Neurosci, 2023
Jwair S, Ramekers D, Thomeer HGXM, Versnel H.   +3 more
europepmc   +1 more source

FURTHER OBSERVATIONS ON RESTING AND ACTION POTENTIAL OF INTRACELLULARLY PERFUSED SQUID AXON [PDF]

, 1962
Ichiji Tasaki, Muneo Shimamura
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Synchronous Measurements of Extracellular Action Potentials and Neurochemical Activity with Carbon Fiber Electrodes in Nonhuman Primates. [PDF]

eNeuro
Amjad U, Choi J, Gibson DJ, Murray R, Graybiel AM, Schwerdt HN.   +5 more
europepmc   +1 more source

The effect of sodium and calcium on the action potential of the smooth muscle of the guinea‐pig taenia coli

, 1969
Alison F. Brading, Edith Bülbring, T. Tomita   +2 more
openalex   +2 more sources