Results 61 to 70 of about 762,494 (319)

The ferroelectric Mott-Hubbard phase of organic (TMTTF)2X conductors [PDF]

open access: yes, 2000
We present experimental evidences for a ferro-electric transition in the family of quasi one- dimensional conductors (TMTTF)2X. We interpret this new transition in the frame of the combined Mott-Hubbard state taking into account the double action of the ...
C. Coulon   +19 more
core   +5 more sources

Dendritic branch structure compartmentalizes voltage-dependent calcium influx in cortical layer 2/3 pyramidal cells

open access: yeseLife, 2022
Back-propagating action potentials (bAPs) regulate synaptic plasticity by evoking voltage-dependent calcium influx throughout dendrites. Attenuation of bAP amplitude in distal dendritic compartments alters plasticity in a location-specific manner by ...
Andrew T Landau   +5 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Abnormal Action Potentials Associated with the Shaker Complex Locus of Drosophila [PDF]

open access: yes, 1981
Intracellular recordings of action potentials were made from the cervical giant axon in Shaker (Sh) mutants and normal Drosophila. The mutants showed abnormally long delays in repolarization.
Ferrus, Alberto   +2 more
core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Genetically Encoded Voltage Indicators Are Illuminating Subcellular Physiology of the Axon

open access: yesFrontiers in Cellular Neuroscience, 2019
Everything we see and do is regulated by electrical signals in our nerves and muscle. Ion channels are crucial for sensing and generating electrical signals.
Lauren C. Panzera, Michael B. Hoppa
doaj   +1 more source

ActionPytential: An open source tool for analyzing and visualizing cardiac action potential data

open access: yesHeliyon, 2023
The action potential forms the basis of cardiac pacemaking, conduction, and contraction. Action potentials can be recorded from numerous preparation types, including ventricular or atrial trabecules, Purkinje fibers, isolated cardiac myocytes.
Tamás Árpádffy-Lovas, Norbert Nagy
doaj   +1 more source

Noncommutative fluid dynamics in the K\"{a}hler parametrization

open access: yes, 2011
In this paper, we propose a first order action functional for a large class of systems that generalize the relativistic perfect fluids in the K\"{a}hler parametrization to noncommutative spacetimes.
A. Connes   +6 more
core   +1 more source

Sampling Properties of the Spectrum and Coherency of Sequences of Action Potentials [PDF]

open access: yes, 2000
The spectrum and coherency are useful quantities for characterizing the temporal correlations and functional relations within and between point processes.
Jarvis, M. R., Mitra, P. P.
core   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

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