Results 151 to 160 of about 8,552,368 (315)

Opportunities for better use of collective action theory in research and governance for invasive species management. [PDF]

open access: yesConserv Biol, 2019
Graham S   +10 more
europepmc   +1 more source

Action Research for Sustainable Development in a Turbulent World: Reflections and Future Perspectives

open access: yes, 2013
The purpose of this article is to reflect on a panel discussion about an edited book launched at the 2012 ALARA Conference in Sydney. The majority of authors participated in the launch discussion and presented the message of their chapters, exploring ...
Dick, Bob   +2 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Theory of action

open access: yes, 2016
Learning results from organizational inquiry.Source: Argyris, C., & Schon, D. A. 1996. Organizational learning II: Theory, method, and practice. Reading, MA: Addison-Wesley.
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Man leaning a ladder against the concrete shuttering of part of a new dam wall which is under construction.

open access: yes, 2015
Project at Bocatoma The Eastern slopes of the Andes in North Peru are among the least developed parts of the country with the majority of people living in remote villages with little or no access to grid electricity.
Practical Action Peru
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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