Results 81 to 90 of about 2,728,969 (283)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
An in-depth statistical analysis of the COVID-19 pandemic’s initial spread in the WHO African region
BMJ Global Health, 2022 Cristina Barroso Hofer +19 more
doaj +1 more source
Givental action and trivialisation of circle action
Journal de l’École polytechnique — Mathématiques, 2015 In this paper, we show that the Givental group action on genus zero cohomological field theories, also known as formal Frobenius manifolds or hypercommutative algebras, naturally arises in the deformation theory of Batalin–Vilkovisky algebras. We prove that the Givental action is equal to an action of the trivialisations of the trivial circle action ...
Dotsenko, Vladimir +2 more
openaire +4 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2011 "While the Adaptive Actions Camp was located in Madrid's Atocha train station for a month during the Madrid Abierto 2010 biennial, a publication was in the works.
Corazón Ardura, José Luis +1 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Macro actions for structures [PDF]
, 2012 It is not surprising that structures underly many of the problems that we find interesting in planning. However, the planners that we develop are not always capable of acting on them as they increase in size.
Lindsay, Alan
core +3 more sources
Action-to-Action Flow Matching
CoRRDiffusion-based policies have recently achieved remarkable success in robotics by formulating action prediction as a conditional denoising process. However, the standard practice of sampling from random Gaussian noise often requires multiple iterative steps to produce clean actions, leading to high inference latency that incurs a major bottleneck for ...
Jindou Jia +7 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Free C+ actions on affine threefolds [PDF]
, 2005 We study algebraic actions of the additive group C+ on an affine threefold X and prove a smoothness property for the quotient morphism X -< X//C+. Then, following Shulim Kaliman, we give a proof of the conjecture that every free C+ action on affine 3 ...
Kraft, H.
core