Results 21 to 30 of about 1,228,320 (303)
Targetable alterations in invasive pleomorphic lobular carcinoma of the breast
Breast Cancer Research, 2021 Background Invasive pleomorphic lobular carcinoma (PLC) of the breast is a subtype of invasive lobular cancer which compromises approximately 1% of all epithelial breast malignancies and is characterized by higher nuclear pleomorphism and poorer ...
Gregory M. Riedlinger +4 more
doaj +1 more source
Anti-CD20 Therapy Acts via FcγRIIIA to Diminish Responsiveness of Human Natural Killer Cells [PDF]
, 2015 Natural killer (NK) immune cells mediate antibody-dependent cellular cytotoxicity (ADCC) by aggregating FcγRIIIA/CD16, contributing significantly to the therapeutic effect of CD20 monoclonal antibodies (mAb).
Capuano, Cristina +8 more
core +1 more source
Activating Methods of Command in the Army
Safety & Defense, 2018 The article presents inspirational methods of command, which might be helpful in the decision making process on the battle- field on tactical and operational levels. The methods allow activating subordinates as well as delegating authority.
Rurak Adam
doaj +1 more source
Regression/eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide. [PDF]
, 2016 Malignant gliomas have poor prognosis and urgently require new therapies. Activating Transcription Factor 5 (ATF5) is highly expressed in gliomas, and interference with its expression/function precipitates targeted glioma cell apoptosis in vitro and in ...
Angelastro, James +11 more
core +2 more sources
Granulocyte-activating mediators (GRAM) [PDF]
, 1988 In the present study we investigated the capability of human epidermal cells to generate granulocyte-activating mediators (GRAM). It could be shown that human epidermal cells as well as an epidermoid carcinoma cell line (A431) produce an epidermal cell ...
Kapp, A. +3 more
core +1 more source
Cancer Cell International, 2023 Background Mutations in the KEAP1-NFE2L2 signaling pathway were linked to increased tumorigenesis and aggressiveness. Interestingly, not all hotspot mutations on NFE2L2 were damaging; some even were activating.
Kewei Wang +12 more
doaj +1 more source
Biomaterials-Mediated Tumor Infarction Therapy
Frontiers in Bioengineering and Biotechnology, 2022 Agents for tumor vascular infarction are recently developed therapeutic agents for the vascular destruction of tumors. They can suppress the progression of the tumor by preventing the flow of nutrition and oxygen to its tissues.
Shizheng Tong +4 more
doaj +1 more source
Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms [PDF]
, 2018 Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces acute proinflammatory responses, but it also induces delayed systemic immunosuppressive effects ...
FitzGerald, Garret A. +6 more
core +1 more source
Nanoparticle Activation Methods in Cancer Treatment [PDF]
Biomolecules, 2019 In this review, we intend to highlight the progress which has been made in recent years around different types of smart activation nanosystems for cancer treatment. Conventional treatment methods, such as chemotherapy or radiotherapy, suffer from a lack of specific targeting and consequent off-target effects.
White, B, Duan, C, Townley, H
openaire +3 more sources
Energy Optimization And Calculation Of Dose Absorption Enhancement Factor In Photon Activation Therapy [PDF]
Iranian Journal of Medical Physics, 2010 Introduction: Secondary radiation such as photoelectrons, Auger electrons and characteristic radiations cause a local boost in dose for a tumor when irradiated with an external X-ray beam after being loaded with elements capable of activating the tumor ...
Hassan Ranjbar +2 more
doaj +1 more source