Results 71 to 80 of about 1,223,681 (299)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Activating Boxmind: an evaluation of a web‐based video lecture with synchronized activities [PDF]

, 2003
The aim of this study was to evaluate the use of synchronous computer‐mediated communication activities in a video e‐lecture. Previous research has reported that learning is facilitated when communication activities are added to a video lecture.
Durkin, Catherine, Joiner, Richard, Morrison, Derek, Williams, Lisa   +3 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Determinants, behaviour change techniques and pedagogical approaches used in secondary school-based food and nutrition programmes: a qualitative study of the SWITCH project

BMC Public Health
Background Food and nutrition programmes at secondary schools have the potential to improve public and planetary health, as they target a wide range of adolescents.
Anouk Mesch, Madelief Engels, Sanne Raghoebar, Laura H. H. Winkens, Judith Gulikers, Renate Wesselink, Annemien Haveman-Nies   +6 more
doaj   +1 more source

A systems biology analysis of brain microvascular endothelial cell lipotoxicity. [PDF]

, 2014
BackgroundNeurovascular inflammation is associated with a number of neurological diseases including vascular dementia and Alzheimer's disease, which are increasingly important causes of morbidity and mortality around the world.
Aung, Hnin H, Rutledge, John C, Tagkopoulos, Ilias, Tsoukalas, Athanasios   +3 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The impact of peroxisome proliferator‐activated receptor‐γ activating angiotensin receptor blocker on outcomes of patients receiving immunotherapy

Cancer Medicine, 2023
Background Certain angiotensin receptor blockers (ARBs) have peroxisome proliferator‐activated receptor‐γ (PPAR‐γ) activation property, which has been associated with improved programmed cell death ligand 1 blockade and cytotoxic T lymphocyte‐mediated ...
Cho‐Han Chiang, Yu‐Cheng Chang, Shih‐Syuan Wang, Yuan‐Jen Chen, Xin Ya See, Chun‐Yu Peng, Yuan Ping Hsia, Cho‐Hsien Chiang, Cho‐Hung Chiang, Cheng‐Ming Peng   +9 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Lipopolysaccharide induces nitric oxide synthase expression and platelet-activating factor increases nitric oxide production in human fetal membranes in culture

Reproductive Biology and Endocrinology, 2004
Background Platelet-activating factor and nitric oxide may be involved in the initiation of human labour as inflammatory mediators. The aim of this study was to test whether platelet-activating factor and lipopolysaccharide were able to induce nitric ...
Seyffarth Gunter, Nelson Paul N, Dunmore Simon J, Rodrigo Nalinda, Murphy Damian J, Carson Ray J   +5 more
doaj   +1 more source

Activation of interferon regulatory factor-3 via toll-like receptor 3 and immunomodulatory functions detected in A549 lung epithelial cells exposed to misplaced U1-snRNA [PDF]

, 2009
U1-snRNA is an integral part of the U1 ribonucleoprotein pivotal for pre-mRNA splicing. Toll-like receptor (TLR) signaling has recently been associated with immunoregulatory capacities of U1-snRNA.
C. D. Sadik, M. Bachmann, J. Pfeilschifter, H. Muhl, Busch, Will, Hoet, Lovgren, Hoffman, Casciola-Rosen, Biggiogera, Malmegrim, Dieker, Rosen, Hof, Vandivier, Bowie, Gantier, Schr  der, Matsumoto, Honda, Yoneyama, Schleimer, M  ller, Sexton, Monks, Dow, Colin, O'neill, Schreiber, Schafer, Taniguchi, Colonna, Tamura, Hemmi, M  hl, Reddy, Sioud, Degen, Sturchier, Gowen, Nagai, Pirher, Platanias, Grumbach, Yu, Chung, Krysko, King, Akbar, Vervoordeldonk, Nikolaus, Wirtz, Hemmer, Katakura, Sel, Fadok, Voll, Moller, O'Garra   +59 more
core   +1 more source