Results 61 to 70 of about 7,197,000 (313)

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

open access: yesCell, 2009
Notch signaling regulates many aspects of metazoan development and tissue renewal. Accordingly, misregulation or loss of Notch signaling underlies multiple human disorders, from developmental syndromes to adult onset diseases and cancer.
Raphael Kopan, M. Ilagan
semanticscholar   +1 more source

Active learning enabled activity recognition [PDF]

open access: yesPervasive and Mobile Computing, 2016
© 2016 IEEE, 2016 IEEE International Conference on Pervasive Computing and Communications (PerCom)
H. M. Sajjad Hossain   +2 more
openaire   +1 more source

Infantile Central Nervous System Juvenile Xanthogranuloma With Somatic CSF1R Mutation Responsive to Imatinib Monotherapy

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Juvenile xanthogranuloma (JXG) of the central nervous system (CNS) is a rare non‐Langerhans cell histiocytosis. CSF1R mutations have been reported for peripheral JXG, but not in CNS JXG. A 3‐month‐old male presented with fever, lymphadenopathy, and macrocephaly with bulging fontanelles.
Sima Vazquez   +8 more
wiley   +1 more source

An activity description language for activity recognition [PDF]

open access: yes2017 International Conference on Internet of Things, Embedded Systems and Communications (IINTEC), 2017
Activity recognition aims at recognizing and understanding the movements, actions, and objectives of mobile objects. These objects can be humans, animals, or simple artefacts. Many important and critical applications such as surveillance or health care require some form of (human) activity recognition.
Sarray, Ines   +4 more
openaire   +2 more sources

Nephrogenic Rests/Nephroblastomatosis in Patients With Unilateral Wilms Tumor Are Not Associated With an Increased Risk of Relapse: An Analysis of Patients Treated on the SIOP‐WT‐2001 Protocol in the SIOP‐UK‐CCLG and SIOP‐GPOH Studies (2001–2022)

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misunderstanding of their diagnostic criteria and terminology.
Gordan M. Vujanić   +5 more
wiley   +1 more source

Non-coding microRNAs for cardiac regeneration: Exploring novel alternatives to induce heart healing

open access: yesNon-coding RNA Research, 2017
In recent years, different studies have revealed that adult mammalian cardiomyocytes have the capacity to self-renew under homeostatic conditions and after myocardial injury.
Elena Garreta   +3 more
doaj   +1 more source

Alternative activation of macrophages: mechanism and functions.

open access: yesImmunity, 2010
The concept of an alternative pathway of macrophage activation has stimulated interest in its definition, mechanism, and functional significance in homeostasis and disease.
S. Gordon, F. Martínez
semanticscholar   +1 more source

Charcoal Activation [PDF]

open access: yesProceedings of the National Academy of Sciences, 1919
Adsorption of Gases by Charcoal—Heat Effect.—The first part of this paper comprises a study of the heat effect on the adsorption of hydrogen and nitrogen by charcoal, and is a continuation of the work of Dr. Harvey B. Lemon1 in which air was used. The charcoal is heated for periods varying from one hour to twenty hours at temperatures from 400° C.
openaire   +4 more sources

Efficient palladium-catalyzed electrocarboxylation enables late-stage carbon isotope labelling

open access: yesNature Communications
Carbon isotope labelling of bioactive molecules is essential for accessing the pharmacokinetic and pharmacodynamic properties of new drug entities. Aryl carboxylic acids represent an important class of structural motifs ubiquitous in pharmaceutically ...
Gabriel M. F. Batista   +8 more
doaj   +1 more source

The effect of metformin on the survival of colorectal cancer patients with type 2 diabetes mellitus

open access: yesScientific Reports, 2022
Evidence from previous studies suggests a protective effect of metformin in patients with colorectal cancer (CRC). The aim of this study was to examine the associations between metformin use and overall survival (OS) and disease-free survival (DFS) in ...
Zeinab Tarhini   +5 more
doaj   +1 more source

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