Results 41 to 50 of about 3,155,671 (268)
ChemistryEuropeA chiral N‐9‐Anth‐PyBidine‐Co(OAc)2 complex catalyzed the kinetically controlled asymmetric Michael/alkylation reaction of 3‐chlorooxindoles with alkylidenemalononitriles to give gem‐dicyano‐spirocyclopropyl oxindoles in a highly diastereo‐ and ...
Takaaki Saito +4 more
doaj +1 more source
Taiyuan Ligong Daxue xuebao, 2022 Four kinds of petroleum coke with different sulfur content were used as raw materials to prepare sulfur and nitrogen co-doped carbon materials by potassium hydroxide activation.
Jiawei WANG +5 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Active learning enabled activity recognition [PDF]
Pervasive and Mobile Computing, 2016 © 2016 IEEE, 2016 IEEE International Conference on Pervasive Computing and Communications (PerCom)
H. M. Sajjad Hossain +2 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Non-coding microRNAs for cardiac regeneration: Exploring novel alternatives to induce heart healing
Non-coding RNA Research, 2017 In recent years, different studies have revealed that adult mammalian cardiomyocytes have the capacity to self-renew under homeostatic conditions and after myocardial injury.
Elena Garreta +3 more
doaj +1 more source
An activity description language for activity recognition [PDF]
2017 International Conference on Internet of Things, Embedded Systems and Communications (IINTEC), 2017 Activity recognition aims at recognizing and understanding the movements, actions, and objectives of mobile objects. These objects can be humans, animals, or simple artefacts. Many important and critical applications such as surveillance or health care require some form of (human) activity recognition.
Sarray, Ines +4 more
openaire +3 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Efficient palladium-catalyzed electrocarboxylation enables late-stage carbon isotope labelling
Nature CommunicationsCarbon isotope labelling of bioactive molecules is essential for accessing the pharmacokinetic and pharmacodynamic properties of new drug entities. Aryl carboxylic acids represent an important class of structural motifs ubiquitous in pharmaceutically ...
Gabriel M. F. Batista +8 more
doaj +1 more source
The effect of metformin on the survival of colorectal cancer patients with type 2 diabetes mellitus
Scientific Reports, 2022 Evidence from previous studies suggests a protective effect of metformin in patients with colorectal cancer (CRC). The aim of this study was to examine the associations between metformin use and overall survival (OS) and disease-free survival (DFS) in ...
Zeinab Tarhini +5 more
doaj +1 more source