Results 91 to 100 of about 4,701,980 (316)

Promotion of physical activity guidelines and behavior change

Journal of Physical Fitness and Sports Medicine, 2015
Physical activity guidelines have been published by governments to increase physical activity at a national level. Such guidelines commonly include behavior change techniques.
Kazuhiro Harada, Yoshio Nakamura
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of NF-kappaB activation in Theileria annulata-infected cloned cell lines is associated with detection of parasite-dependent IKK signalosomes and disruption of the actin cytoskeleton [PDF]

, 2010
Apicomplexan parasites within the genus <i>Theileria</i> have the ability to induce continuous proliferation and prevent apoptosis of the infected bovine leukocyte.
Weir, W., Hermann, P., McKellar, S., Dobbelaere, D., Dobbelaere, Dirk,, Schmuckli-Maurer, J., Pillai, S., Shiels, B., Kinnaird, J.   +8 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Characterization of PM₁₀ Sampled on the Top of a Former Mining Tower by the High-Volume Wind Direction-Dependent Sampler Using INNA

Atmosphere, 2020
The PM10 concentrations in the studied region (Ostravsko-karvinská agglomeration, Czech Republic) exceed air pollution limit values in the long-term and pose a significant problem for human health, quality of life and the environment.
Irena Pavlíková, Daniel Hladký, Oldřich Motyka, Konstantin N. Vergel, Ludmila P. Strelkova, Margarita S. Shvetsova   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

On mandatory activation of welfare receivers [PDF]

This paper investigates whether mandatory activation programs for welfare receivers have effects on welfare participation, employment and disposable income. In contrast to earlier studies we are able to capture both entry and exit effects.
Dahlberg, Matz, Mörk, Eva, Johansson, Kajsa   +2 more
core  

Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines [PDF]

, 2009
Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis on binding to its receptors, death receptor 4 and 5 (DR4, DR5).
M Keane, Mehmet, H, A Samali, D Mahalingam, H Mehmet, Mahalingam, D, E Szegezdi, Szegezdi, E, Keane, M, G Pirianov, Pirianov, G, Samali, A   +11 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation [PDF]

, 2012
Because of their outstanding physical properties, carbon nanotubes (CNTs) are promising new materials in the field of nanotechnology. It is therefore imperative to assess their adverse effects on human health.
Dardenne, Christophe, Meunier, Etienne, Bernard Pipy, David Olagnier, José Bernad, Agnès Coste, Authier, Hélène, Emmanuel Flahaut, Béraud, Maryse, Bernad, José, Flahaut, Emmanuel, Etienne Meunier, Maryse Béraud, Pipy, Bernard, Lise Lefèvre, Christophe Dardenne, Coste, Agnès, Hélène Authier, Olagnier, David, Lefèvre, Lise   +19 more
core   +1 more source