Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Activation Likelihood Estimation Neuroimaging Meta-Analysis: a Powerful Tool for Emotion Research
Psychology Research and Behavior ManagementTommaso Costa,1,2 Mario Ferraro,1– 3 Jordi Manuello,1,2 Alessia Camasio,2,3 Andrea Nani,2 Lorenzo Mancuso,2 Franco Cauda,1,2 Peter T Fox,4,5 Donato Liloia1,2 1GCS-fMRI, Koelliker Hospital and Department of Psychology, University of Turin, Turin, Italy ...
Costa T +8 more
doaj
Late Pleistocene pottery production and exchange: Provenance studies of hunter-gatherer wares from southern Kyushu, Japan by neutron activation analysis. [PDF]
PLoS One, 2022 Iizuka F, Ferguson JR, Izuho M.
europepmc +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity [PDF]
, 2003 A reduction in microglial activation and subsequent neurotoxicity may prove critical for neuroprotection in neurodegenerative diseases. We examined the expression and functionality of group III metabotropic glutamate (mGlu) receptors on microglia.
Taylor, D.L., Pocock, J.M., Diemel, L.T.
core
NeuroImage: ClinicalThe past decade has seen an increased interest in the cerebellum, particularly in non-motor behaviors. Emerging work across model systems and in humans has also implicated the cerebellum in Alzheimer’s Disease (AD) and in mild cognitive impairment (MCI).
Jessica A. Bernard +8 more
doaj +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Combined homologous recombination repair deficiency and immune activation analysis for predicting intensified responses of anthracycline, cyclophosphamide and taxane chemotherapy in triple-negative breast cancer. [PDF]
BMC Med, 2021 Liao G +11 more
europepmc +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Statistical Approach and Neutron Activation Analysis for Determining Essential and Toxic Elements in Two Kinds of Algerian Artemisia Plant. [PDF]
Biol Trace Elem Res, 2021 Begaa S, Messaoudi M, Benarfa A.
europepmc +1 more source