Results 51 to 60 of about 60,175,050 (353)

Activation of human NK cells by Plasmodium-infected red blood cells.

open access: yes, 2012
This chapter describes a protocol to assess activation of human NK cells following in vitro stimulation with malaria-infected red blood cells. Activation is assessed by flow cytometry, staining for cell surface expression of CD69 and accumulation of ...
Riley, Eleanor M   +3 more
core   +1 more source

Single-molecule analysis of ligand efficacy in β2AR-G protein activation

open access: yesNature, 2017
G-protein-coupled receptor (GPCR)-mediated signal transduction is central to human physiology and disease intervention, yet the molecular mechanisms responsible for ligand-dependent signalling responses remain poorly understood.
G. G. Gregorio   +13 more
semanticscholar   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen   +10 more
wiley   +1 more source

T-Cell activation: a queuing theory analysis at low agonist density [PDF]

open access: yes, 2006
We analyze a simple linear triggering model of the T-cell receptor (TCR) within the framework of queuing theory, in which TCRs enter the queue upon full activation and exit by downregulation.
Burroughs, Nigel John, Wedagedera, J. R.
core   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko   +5 more
wiley   +1 more source

Detecting Safety Training Modification in Language Models via Activation Analysis

open access: yesIEEE Access
We introduce AMS (Activation-based Model Scanner), a tool that detects modifications to safety training in language models by measuring the geometric structure of safety-relevant concepts in activation space. Safety training creates measurable separation
Glen Messenger
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess   +5 more
wiley   +1 more source

Moss Technique Used to Monitor the Atmospheric Deposition of Trace Elements on the Territory of the Ryazan Region, Russia

open access: yesAtmosphere
Instrumental neutron activation analysis in combination with the method of moss biomonitoring for the assessment of atmospheric deposition of heavy metals and other elements was applied for the first time in the Ryazan Region in Russia. Concentrations of
Eleonora Blinova   +3 more
doaj   +1 more source

Neutron Activation Analysis characterization procedures for fish consumed at São Paulo City

open access: yesBrazilian Journal of Radiation Sciences, 2019
The characterization of edible tissues of fishes consumed by humans is very important for determination of several toxic and potentially toxic elements, ensuring the food safety.
Bruno Tappiz, Edson Gonçalves Moreira
doaj   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga   +3 more
wiley   +1 more source

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