Results 51 to 60 of about 60,175,050 (353)
Activation of human NK cells by Plasmodium-infected red blood cells.
This chapter describes a protocol to assess activation of human NK cells following in vitro stimulation with malaria-infected red blood cells. Activation is assessed by flow cytometry, staining for cell surface expression of CD69 and accumulation of ...
Riley, Eleanor M +3 more
core +1 more source
Single-molecule analysis of ligand efficacy in β2AR-G protein activation
G-protein-coupled receptor (GPCR)-mediated signal transduction is central to human physiology and disease intervention, yet the molecular mechanisms responsible for ligand-dependent signalling responses remain poorly understood.
G. G. Gregorio +13 more
semanticscholar +1 more source
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen +10 more
wiley +1 more source
T-Cell activation: a queuing theory analysis at low agonist density [PDF]
We analyze a simple linear triggering model of the T-cell receptor (TCR) within the framework of queuing theory, in which TCRs enter the queue upon full activation and exit by downregulation.
Burroughs, Nigel John, Wedagedera, J. R.
core +1 more source
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
Detecting Safety Training Modification in Language Models via Activation Analysis
We introduce AMS (Activation-based Model Scanner), a tool that detects modifications to safety training in language models by measuring the geometric structure of safety-relevant concepts in activation space. Safety training creates measurable separation
Glen Messenger
doaj +1 more source
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess +5 more
wiley +1 more source
Instrumental neutron activation analysis in combination with the method of moss biomonitoring for the assessment of atmospheric deposition of heavy metals and other elements was applied for the first time in the Ryazan Region in Russia. Concentrations of
Eleonora Blinova +3 more
doaj +1 more source
Neutron Activation Analysis characterization procedures for fish consumed at São Paulo City
The characterization of edible tissues of fishes consumed by humans is very important for determination of several toxic and potentially toxic elements, ensuring the food safety.
Bruno Tappiz, Edson Gonçalves Moreira
doaj +1 more source
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga +3 more
wiley +1 more source

