Results 261 to 270 of about 4,534,827 (376)

Exploring the selective inhibitory effects of Flavoxate and its analogues on two chloride channels and neuronal action potentials. [PDF]

Korean J Physiol Pharmacol
Zhang G, Zhou A, Liu J, Wang J, Yang J, Cui Y, Zhao Y, Song Y, Li Y, Li H, Zhang X, Zhang Y.   +11 more
europepmc   +1 more source

Biohybrid Tendons Enhance the Power‐to‐Weight Ratio and Modularity of Muscle‐Powered Robots

Advanced Science, EarlyView.
Biohybrid robots powered by skeletal muscle actuators are capable of dynamically adapting to environmental cues. This study takes inspiration from native muscle–tendon architecture by leveraging tough hydrogels as synthetic tendons for muscle actuators to enhance the power‐to‐weight ratio and modularity of biohybrid machines.
Nicolas Castro, Ronald Heisser, Maheera Bawa, Bastien Aymon, Sarah Wu, Annika Marschner, Sonika Kohli, Angel Bu, Laura Rosado, Martin Culpepper, Xuanhe Zhao, Ritu Raman   +11 more
wiley   +1 more source

In silico docking yields small molecule negative allosteric modulators targeting the core of Frizzled 7. [PDF]

Nat Commun
Scharf MM, Kinsolving J, Grätz L, Voss JH, Carrasco-Busturia D, Forsberg B, Kolb P, Schulte G.   +7 more
europepmc   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Recent advances in mycobacterial transcription: insights beyond the general pathway. [PDF]

J Bacteriol
Hazra N, Mukhopadhyay J.
europepmc   +1 more source

Stratégie de suivi de creux de tension pour convertisseur Flyback active-clamp

, 2016
Sébastien Larousse, Hubert Razik, Rémy Cellier, Nacer Abouchi, Philippe Volay   +4 more
openalex   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

PRECONDITIONING OF PORCINE FLEXOR TENDONS FOR APPLICATION IN RECONSTRUCTION OF HAND FLEXOR TENDONS. [PDF]

Acta Ortop Bras
Iamaguchi RB, Pereira CAM, Dos Santos GB, do Nascimento FES, da Costa HPV, Mattar R.   +5 more
europepmc   +1 more source

A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation

, 2006
Roman A. Melnyk, R. John Collier
openalex   +1 more source

Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning

Advanced Science, EarlyView.
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao, Guiyuan Shi, Ruixue Qin, Yinghao Sun, Wenbo Guo, Ruixia Shi, Minxian Peng, Jingxuan Yang, Jianjian Zhao, Qiuhan Liu, Jun Xiao, Ke Zhang, Qiang Liu, Wenxing Yang, He Liu   +14 more
wiley   +1 more source