Actively Induced Supercoiling Can Slow Down Plasmid Solutions by Trapping the Threading Entanglements. [PDF]
Staňo R, Rusková R, Račko D, Smrek J.
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Novel Quantitative OCTA Biomarkers of Choroidal Neovascularization and Associations With Disease Activity and Etiology. [PDF]
Gan Y +7 more
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Mavacamten inhibits myosin activity by stabilizing the myosin interacting-heads motif and stalling motor force generation. [PDF]
McMillan SN +4 more
europepmc +1 more source
Computational modeling of spatiotemporal afterimage visual perception with spiking neural networks. [PDF]
Byzalov I, Cohen Duwek H, Ezra Tsur E.
europepmc +1 more source
Automatic Polygon Annotation of Plant Objects for Training Dataset Preparation in Green Biomass Segmentation Tasks. [PDF]
Ivliev E +3 more
europepmc +1 more source
Alcalase hydrolysis modulates the techno-functional properties of dry-fractionated pea protein, reduces the off-flavor compounds and refines the aroma profile. [PDF]
Falotico D +8 more
europepmc +1 more source

