Results 171 to 180 of about 2,835,652 (315)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Practicing Active Control of Thumb Force Alters the Excitability of Anterior Horn Cells of the Spinal Cord. [PDF]

Cureus
Mizoguchi A, Kiyohara K, Kado N, Suzuki T.   +3 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Active control of forward/backward charge transfer in Z-scheme water splitting: manipulating electrostatic affinity/repulsion between photocatalyst surface and electron mediator. [PDF]

Chem Sci
Itagaki R, Nakada A, Suzuki H, Tomita O, Abe R.   +4 more
europepmc   +1 more source

Using Deep Reinforcement Learning for Active Flow Control

, 2020
Marius Holm
openalex   +1 more source

STUDIES ON ACTIVE CONTROL OF STRUCTURES USING HYPER VISION TECHNOLOGY

, 2010
Hideharu Nakamura, Tokuo Tsuji, Idaku Ishii, Ryouichi SATAKE, Takeshi Nakayama, Junichiro MOTOYAMA   +5 more
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Active control of electroacoustic resonators in the audible regime: control strategies and airborne applications. [PDF]

NPJ Acoust
Malléjac M, Volery M, Lissek H, Fleury R.   +3 more
europepmc   +1 more source

Mid-term outcomes of microfragmented adipose tissue plus arthroscopic surgery for knee osteoarthritis: A randomized, active-control, multicenter clinical trial. [PDF]

World J Stem Cells, 2023
Wu CZ, Shi ZY, Wu Z, Lin WJ, Chen WB, Jia XW, Xiang SC, Xu HH, Ge QW, Zou KA, Wang X, Chen JL, Wang PE, Yuan WH, Jin HT, Tong PJ.   +15 more
europepmc   +1 more source

THE APPLICATION OF SIMPLE SOURCE THEORY TO ACTIVE NOISE CONTROL [PDF]

I.G. Brown
openalex   +1 more source