Advanced Science, EarlyView.An endoplasmic reticulum (ER)‐targeted chemodynamic nanoagent (TCBQ/iLD‐ER NPs) comprising •OH‐generating tetrachloro‐1,4‐benzoquinone (TCBQ) and lipid droplets (LDs) formation inhibitor (iLD) is developed for chemodynamic immunotherapy of tumors. After ingestion by cancer cells, TCBQ/iLD‐ER NPs preferentially accumulate in the ER and react with ER ...
Huilan Cai +12 more
wiley +1 more source
A phase correction frequency selector for enhanced switching accuracy in SH-ADD semi-active suspension. [PDF]
Sci RepZhao J, Su F, Feng J, Fan W, Zhuang Y.
europepmc +1 more source
2017 R&D 100 Award Winner: Control System for Active Damping of Inter-Area Oscillations.
, 2019 David Schoenwald
openalex +1 more source
Advanced Science, EarlyView.ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen +7 more
wiley +1 more source
Sound Insulation Mechanism and Multi-Field Regulation of MXene Dielectric-Tunable Subwavelength Piezoelectric Metamaterials. [PDF]
Materials (Basel)Cao P, Zhao X, Mei C, Ma X.
europepmc +1 more source
Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy
Advanced Science, EarlyView.ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang +10 more
wiley +1 more source
Development of a novel pendulum column base isolation system with vertical negative stiffness (PC-VNS) for pile-like behavior for seismic applications. [PDF]
Sci RepAzizi A, Barghian M.
europepmc +1 more source
Mixing‐Driven Defects and Composition Evolution in Multi‐Material Metal Additive Manufacturing
Advanced Science, EarlyView.Operando synchrotron X‐ray imaging coupled with high‐fidelity multiphysics modeling uncovers how inter‐material mixing reshapes keyhole dynamics and drives distinct pore‐formation pathways in multi‐material laser powder bed fusion (LPBF). Composition‐dependent instabilities trigger defects, whereas rescanning suppresses porosity and homogenizes Cu ...
Zhilang Zhang +5 more
wiley +1 more source
An Active Spring Mass Model With Biomimetic Ground Reaction Forces for Multiple Terrains. [PDF]
IEEE Trans Biomed EngKumar S, Geyer H.
europepmc +1 more source