Results 211 to 220 of about 4,313,187 (347)
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Manufacturing Supply Chains and Imports in the ADHD Drug Shortage.
Currie J, Malinovskaya A.
europepmc +1 more source
Full-Photolithographic High-Density Skin-Like Transistor Arrays for All-Organic Active-Matrix Displays. [PDF]
Xue P +17 more
europepmc +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Supply-demand governance of hierarchical healthcare systems: mobile big data unveils non-random patient flow patterns and the bypass premium in cities. [PDF]
Guo Q, Ren H, Shao X.
europepmc +1 more source
Active Network Management for Electrical Distribution Systems
With the increasing share of renewable and distributed generation in electrical distribution systems, Active Network Management (ANM) has become a valuable option for a distribution system operator to operate his system in a secure and cost-effective way without relying solely on network reinforcement.
openaire +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source

