Results 171 to 180 of about 43,324 (238)

Integrated In Vitro, In Vivo, and In Silico Study Reveals Gut‐Protective Effects of Myricitrin From Chinese Bayberry Leaves

open access: yesFood Frontiers, EarlyView.
High‐purity myricitrin from Chinese bayberry leaves alleviates colonic inflammation by preserving epithelial barrier integrity and reshaping gut microbiota composition. ABSTRACT Polyphenols have been widely recognized for their ability to modulate the host inflammatory response and orchestrate the intestinal microenvironment.
Ji‐Min Lv   +7 more
wiley   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

open access: yesFood Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao   +8 more
wiley   +1 more source

Prophylactic protection from lethal henipavirus disease mediated by Nipah-derived defective interfering particles is influenced by challenge virus strain and viral species. [PDF]

open access: yesEBioMedicine
Welch SR   +11 more
europepmc   +1 more source

Isorhamnetin Alleviates Renal Fibrosis Induced by Renal Tubular Epithelial Cell Senescence Via Inhibition of the IL‐6/IL‐6R Signaling Pathway

open access: yesiMetaMed, EarlyView.
IL‐6 from RTECs upregulates TGF‐β in macrophages, promoting fibroblast transdifferentiation. Isorhamnetin inhibits this effect. ABSTRACT Chronic kidney disease (CKD) is a major global health issue. Kidney fibrosis is a key mechanism leading to end‐stage renal disease.
Weifei Liang   +8 more
wiley   +1 more source

[Active voluntary euthanasia].

open access: yesTidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1991
openaire   +1 more source

Plant‐derived extracellular vesicle‐like particles as novel osteoanabolic agents: Activating bone morphogenetic protein 2/Smads signaling axis for bone regeneration in postmenopausal osteoporosis

open access: yesInterdisciplinary Medicine, EarlyView.
Illustration depicting the isolation of Dipsaci Radix derived extracellular vesicle‐like particles and their function in alleviating osteoporosis. (A) Extraction and characterization detection process of extracellular vesicle‐like particles derived from Dipsaci Radix roots. (B) Cell experiments in vitro, Dipsaci Radix derived extracellular vesicle‐like
Qing Zhao   +12 more
wiley   +1 more source

[On active euthanasia].

open access: yesTidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1996
openaire   +1 more source

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