Results 31 to 40 of about 3,412,364 (301)

Euthanasia and Related Practices Worldwide

open access: yes, 1998
The present paper examines the occurrence of matters relating to the ending of life, including active euthanasia, which is, technically speaking, illegal worldwide.
Kelleher, Michael J.   +4 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

The Juridical Impications Of Withdrawal Life-Support In Hospital in Indonesia

open access: yesJurnal Profesi Medika, 2021
Withdrawal life-support is mainly categorized as part of euthanasia. When viewed from the aspect of criminal law in force in Indonesia, Indonesia does not permit active euthanasia by anyone (including doctors and medics). If the doctor ends the patient’s
Isniani Ramadhani, Sekar Prabarini
doaj   +1 more source

Suicide and Voluntary Active Euthanasia: Why the Difference in Attitude?

open access: yes, 1995
It appears that the attitudes of health professionals differ towards suicide and voluntary active euthanasia. An acceptance of, if not an agreement with, voluntary active euthanasia exists, while there is a general consensus that suicide should be ...
Beech, Ian
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

The Self-Stranding Behavior of a Killer Whale (Orcinus orca) in Inner Danish Waters and Considerations concerning Human Interference in Live Strandings

open access: yesAnimals, 2023
The rescue attempts of stranded whales and euthanasia considerations must include condition assessments of the individual involved, but this is challenged by our insufficient knowledge about the health statuses of these whales.
Aage Kristian Olsen Alstrup   +10 more
doaj   +1 more source

A Case Against Dutch Euthanasia

open access: yes, 1989
The growing acceptance of voluntary active euthanasia by the Dutch is examined in relation to the plastic cards requesting active euthanasia carried by many people in The Netherlands, public opinion polls, and support by leading medical figures of the ...
Fenigsen, Richard
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Legal Developments Concerning Active Euthanasia on Request in the Netherlands

open access: yes, 1987
The author describes social and legal developments in the debate over active euthanasia in the Netherlands. There, as in all of Western Europe, euthanasia is a crime. Although the medical profession in several European countries has rejected efforts to
Gevers, J.K.M.
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

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