Results 71 to 80 of about 3,412,364 (301)

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Attitudes Toward Active Voluntary Euthanasia Among Community-Dwelling Older Subjects

open access: yesSAGE Open, 2018
The major extension of late-life expectancy has increased the significance of end-of-life issues, particularly among elderly people, considering both the role of medical practices in shaping and defining dying trajectories and the differences in national
Stefano Poli
doaj   +1 more source

Four Newly Established Legal Requisites for Active Euthanasia in Japan

open access: yes, 1996
On March 28, 1995 at the Yokohama District Court in Japan, four legal requisites for active euthanasia were newly established by the chief judge, when he rendered the judgment on the murder case of a physician, Tokunaga. The case has been reported by the
Hoshino, Kazumasa
core  

Changing Attitudes Towards Euthanasia Among Medical Students in Austria

open access: yes, 2011
In most European countries the attitudes regarding the acceptability of active euthanasia have clearly changed in the population since World War II.
Freidl, Wolfgang   +3 more
core   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han   +24 more
wiley   +1 more source

Euthanasia in the Major World Religions [PDF]

open access: yesاخلاق وحیانی, 2015
“Euthanasia” or voluntary termination of life is one the most complicated issues in the moral, legal and religious debates nowadays. In the meantime, the role of religions in directing the views of researchers is obvious. In this article, a brief look at
Angeliki Ziaka
doaj  

Euthanasia and the Healthcare Professional

open access: yes, 1995
Euthanasia, often called mercy killing, is the act of inducing death often on terminally ill individuals for reasons assumed to be merciful. Euthanasia can be active or passive, and voluntary or involuntary.
Nnadi-Okolo, Eucharia E.
core  

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

open access: yesAdvanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu   +7 more
wiley   +1 more source

Euthanasia

open access: yes, 1996
This article provides a brief review of the history of euthanasia. The problems involved in withholding or withdrawing treatment, physician-assisted suicide, and arguments for or against euthanasia are discussed.
Nyman, Deborah J.   +2 more
core   +1 more source

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