Results 61 to 70 of about 505,709 (247)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Engineering unsteerable quantum states with active feedback

Physical Review Research
We propose active steering protocols for quantum state preparation in quantum circuits where each system qubit is connected to a single detector qubit, employing a simple coupling selected from a small set of steering operators. The decision is made such
Samuel Morales, Yuval Gefen, Igor Gornyi, Alex Zazunov, Reinhold Egger   +4 more
doaj   +1 more source

Active Learning with Partial Feedback

, 2018
ICLR ...
Hu, Peiyun, Lipton, Zachary C., Anandkumar, Anima, Ramanan, Deva   +3 more
openaire   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

An Improved Force Feedback Control Algorithm for Active Tendons

Sensors, 2012
An active tendon, consisting of a displacement actuator and a co-located force sensor, has been adopted by many studies to suppress the vibration of large space flexible structures.
Ligang Cai, Zhifeng Liu, Tieneng Guo
doaj   +1 more source

Implementation of an in situ simulation-based training adapted from Morbidity and Mortality conference cases: effect on the occurrence of adverse events—study protocol of a cluster randomised controlled trial

Trials, 2022
Background Morbidity and Mortality conference provides the necessary improvement measures for patient safety. However, they are an underused resource mainly because the conclusions to be drawn from the discussion and their implications for practice are ...
Nicolas Michel, Bernard Bui-Xuan, Lionel Bapteste, Thomas Rimmele, Marc Lilot, François Chollet, Hélène Favre, Antoine Duclos, Philippe Michel   +8 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A Four-Stage Method for Active Control with Online Feedback Path Modelling Using Control Signal

Applied Sciences, 2019
The presence of control signal feedback to the reference microphone in feedforward active control systems deteriorates the control performance. A four-stage method is proposed in this paper to carry out online feedback path modelling with the control ...
Somanath Pradhan, Xiaojun Qiu, Jinchen Ji   +2 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Static output feedback control for active suspension system with input delay and parameter uncertainty

Advances in Mechanical Engineering, 2018
This article focuses on static output feedback H ∞ control for active suspension system with input delay and parameter uncertainty. The parameter uncertainty of active suspension system model, input delay of actuator, input disturbance of road, and ...
Kuiyang Wang, Ping He, Jinhua Tang, Jiangcheng Chen   +3 more
doaj   +1 more source