Results 81 to 90 of about 15,627,696 (292)

Effects of Input Voltage and Freestream Velocity on Active Flow Control of Passage Vortex in a Linear Turbine Cascade Using Dielectric Barrier Discharge Plasma Actuator

open access: yesEnergies, 2020
Passage vortex exists as one of the typical secondary flows in turbomachines and generates a significant total pressure loss and degrades the aerodynamic performance. Herein, a dielectric barrier discharge (DBD) plasma actuator was utilized for an active
Takayuki Matsunuma, Takehiko Segawa
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Damage Tolerant Active Contro l: Concept and State of the Art [PDF]

open access: yes, 2012
Damage tolerant active control is a new research area relating to fault tolerant control design applied to mechanical structures. It encompasses several techniques already used to design controllers and to detect and to diagnose faults, as well to ...
NOBREGA, Euripedes, MECHBAL, Nazih
core  

Active control of flow and heat transfer in silicon microchannels

open access: yes, 2010
Boiling heat transfer in silicon microchannels needs high walls and liquid superheats for bubble nucleation, leading to a strong thermal non-equilibrium between vapor and liquid phases, which not only damages the heat transfer device at the start-up ...
Zhang, Andwei   +3 more
core   +1 more source

Special Issue “Active Flow Control Processes with Machine Learning and the Internet of Things”

open access: yes, 2023
The desired changes in flow characteristics are obtained by flow control, which implies manipulating flow behavior such as drag reduction, mixing augmentation, or noise attenuation, employing active or passive devices [...
Valentina Emilia Balas   +2 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Fluid flow between active elastic plates [PDF]

open access: yes, 2009
We propose a model of a channel flow between actively moving elastic plates as a framework for blood flow in active human arteries. The main difference from extant models is that our model is autonomous.
Strunin, D. V.
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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