Results 181 to 190 of about 15,679,398 (295)

Geometric control of active flows

open access: yes
The development of an organism starting from a fertilized egg involves the self-organized formation of patterns and the generation of shape. Patterns and shapes are characterized by their geometry, i.e. angles and distances between features. In this thesis, we set out to understand how the given geometry of pattern and shape of a living system feeds ...
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Pumppustrategian kehittäminen : case : Valmet Flow Control Oy

open access: yes
Opinnäytetyössä selvitettiin Valmet Flow Control Oy:n toimeksiannosta pumppustrategian kehittämiselle lähtötietoja. Toimeksiantaja on toiminut venttiililiiketoiminnassa vuosikymmeniä ja pumppuliiketoiminnan tullessa yrityskaupan yhteydessä mukaan ...
Rossi, Markus
core  

Early active normothermia versus no temperature control in a porcine model of extracorporeal cardiopulmonary resuscitation. [PDF]

open access: yesIntensive Care Med Exp
de Roux Q   +13 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

An acute crossover trial of passive movement training with and without blood flow restriction to determine the impact on postprandial glycaemia. [PDF]

open access: yesExp Physiol
Railton-Sowerby J   +8 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

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