Results 101 to 110 of about 1,002,819 (265)

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

Active and Passive Flow Control of Turbomachines

open access: yesInternational Journal of Rotating Machinery, 2013
N. Sitaram   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Effects of Fixed Leading-Edge DBD Plasma Actuation on Pressure-Derived Lift of a NACA 0012 Airfoil

open access: yesAerospace
In this study, a dielectric barrier discharge (DBD) plasma actuator was placed at the leading edge of a National Advisory Committee for Aeronautics (NACA) 0012 airfoil to act on the separation initiation point, rather than on an already separated flow ...
Takafumi Yamada, Daiki Kishimoto
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Active Flow Control Activities at NASA Langley [PDF]

open access: yes2nd AIAA Flow Control Conference, 2004
Scott Anders   +2 more
openaire   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Contribution à l'étude du contrôle actif de l’écoulement autour d’un profil de pale d’éolienne

open access: yesRevue des Énergies Renouvelables, 2015
Cette étude a pour objectif l’amélioration des caractéristiques aérodynamiques d’un profil de pale d’éolienne par l’utilisation d’une technique de contrôle actif de l’écoulement.
A. Boudis   +3 more
doaj  

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

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