Results 51 to 60 of about 1,024,804 (310)

Reinforcement Learning for Active Flow Control in Experiments

CoRR, 2020
We demonstrate experimentally the feasibility of applying reinforcement learning (RL) in flow control problems by automatically discovering active control strategies without any prior knowledge of the flow physics. We consider the turbulent flow past a circular cylinder with the aim of reducing the cylinder drag force or maximizing the power gain ...
Dixia Fan, Liu Yang 0027, Michael S. Triantafyllou, George Em Karniadakis   +3 more
openaire   +2 more sources

Magnetically Actuated Microvalves for Active Flow Control [PDF]

Journal of Physics: Conference Series, 2006
The reattachment of separated air flows can be actively controlled by blowing oscillatory air jets in the boundary layer, through submillimetric holes situated near the separation edge. To achieve such pulsed jets, a high flow rate, high actuation frequency microvalve was designed, fabricated and characterized.
Ducloux, Olivier, Deblock, Yves, Talbi, Abdelkrim, Gimeno, Leticia, Tiercelin, Nicolas, Pernod, Philippe, Preobrazhensky, Vladimir L., Merlen, Alain   +7 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Progress of active flow control aircraft adopting rudderless flight control and STOL

Advances in Aerodynamics
Active flow control aircraft (AFCA) represent a significant development direction in next-generation aircraft design. Among them, rudderless flight control (RFC) and short takeoff and landing (STOL) are gaining widespread attentions and are gradually ...
Zhijie Zhao, Zhenbing Luo, Xiong Deng, Jianyuan Zhang, Yan Zhou, Wenqiang Peng, Yanbin Feng   +6 more
doaj   +1 more source

Quantitative Analysis of Drag Reduction Methods for Blunt Shaped Automobiles

Applied Sciences, 2020
In fluid mechanics, drag related problems aim to reduce fuel consumption. This paper is intended to provide guidance for drag reduction applications on cars.
Ferenc Szodrai
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Investigations on the Potentials of Novel Technologies for Aircraft Fuel Burn Reduction through Aerostructural Optimisation

Aerospace, 2022
A physics-based optimisation framework is developed to investigate the potential advantages of novel technologies on the energy efficiency of a midrange passenger aircraft.
Valerio Mosca, Ali Elham
doaj   +1 more source

Active Vibration Control for a CNC Milling Machine

, 2013
There is a requirement for improved three-dimensional surface characterisation and reduced tool wear when modern computer numerical control (CNC) machine tools are operating at high cutting velocities, spindle speeds and feed rates.
Longstaff, Andrew P., Myers, A., Lockwood, S., Longstaff, A., Haase, Frerk, Haase, F., Ford, Derek G., Ford, D. G., Myers, Alan, Lockwood, Stephen   +9 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source