Results 91 to 100 of about 89,220 (323)

Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells‐Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation

open access: yesAdvanced Science, EarlyView.
This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li   +9 more
wiley   +1 more source

Powerful outflows in the central parsecs of the low-luminosity active galactic nucleus NGC 1386 [PDF]

open access: yes, 2017
Low-luminosity Active Galactic Nuclei, i.e. L_bol/L_edd ~ 10^-6 - 10^-3, constitute the bulk population of Active Galactic Nuclei (AGNs). Powerful jets, common in these objects, are a crucial source of feedback energy driving mass outflows into the host ...
A. Rodr'iguez-Ardila   +14 more
semanticscholar   +1 more source

Leukemic Cells Hijack Stromal Bioelectricity to Reprogram the Bone Marrow Niche via CaV1.2‐Dependent Mechanisms

open access: yesAdvanced Science, EarlyView.
Leukemic blasts induce membrane depolarization in mesenchymal stromal cells (MSCs), contributing to a dysfunctional niche that favors leukemia progression. Here, it is demonstrated that restoring the expression of CaV1.2 calcium channel in AML‐MSCs repolarizes their membrane potential, reprogramming them toward a healthy phenotype.
Ambra Da Ros   +11 more
wiley   +1 more source

Extremely Red Galaxies at z = 5–9 with MIRI and NIRSpec: Dusty Galaxies or Obscured Active Galactic Nuclei?

open access: yesAstrophysical Journal
We study a new population of extremely red objects (EROs) recently discovered by the James Webb Space Telescope (JWST) based on their NIRCam colors F277W − F444W > 1.5 mag.
G. Barro   +33 more
semanticscholar   +1 more source

ACTIVE GALACTIC NUCLEUS FEEDBACK IN THE HOT HALO OF NGC 4649

open access: yesThe Astrophysical Journal, 2014
Using the deepest available Chandra observations of NGC 4649, we find strong evidences of cavities, ripples, and ring-like structures in the hot interstellar medium that appear to be morphologically related with the central radio emission. These structures show no significant temperature variations in correspondence with higher pressure regions (0.5 ...
Paggi, Alessandro   +6 more
openaire   +4 more sources

Millikelvin Intracellular Nanothermometry with Nanodiamonds

open access: yesAdvanced Science, EarlyView.
Nanothermometry in living cells is crucial for understanding heat diffusion and advancing cellular biology and drug discovery. Previous studies have reported controversial intracellular temperature variations. Using nanodiamond nanothermometry in macrophages, it is found that, in such experimental setting, apparent temperature changes are actually due ...
Maabur Sow   +26 more
wiley   +1 more source

HST/WFC3 Observations of an Off-Nuclear Superbubble in Arp 220 [PDF]

open access: yes, 2015
We present a high spatial resolution optical and infrared study of the circumnuclear region in Arp 220, a late-stage galaxy merger. Narrowband imaging using HST/WFC3 has resolved the previously observed peak in H$\alpha$+[NII] emission into a bubble ...
Allen, Mark G.   +11 more
core   +1 more source

The weak Fe fluorescence line and long-term X-ray evolution of the Compton-thick active galactic nucleus in NGC 7674 [PDF]

open access: yes, 2016
We present NuSTAR X-ray observations of the active galactic nucleus (AGN) in NGC 7674. The source shows a flat X-ray spectrum, suggesting that it is obscured by Compton-thick gas columns.
P. Gandhi   +36 more
semanticscholar   +1 more source

Calorimetry of Active Galactic Nucleus jets: testing plasma composition in Cygnus A

open access: yes, 2012
We examine plasma composition of jets in active galactic nuclei through the comparison of the total pressure ($P$) with partial pressures of electrons and protons in a cocoon.
Amato   +64 more
core   +1 more source

A Hubble Space Telescope Imaging Survey of Nearby Active Glactic Nuclei [PDF]

open access: yes, 1998
We obtained 500-second F606W WFPC2 images of 256 of the nearest ...
Antonucci R.   +9 more
core   +2 more sources

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