Engineering Gypsophila elegans hairy root cultures to produce endosomal escape‐enhancing saponins
Summary The limited cytosolic delivery of DNA and protein‐based therapeutics due to endosomal entrapment reduces drug efficacy, increasing treatment costs and possible side effects in human and veterinary medicine as a consequence of higher administered dosages.
Elia Lacchini+4 more
wiley +1 more source
Factors Determining Variability Time in Active Galactic Nucleus Jets [PDF]
AbstractThe relationship between observed variability time and emission region geometry is explored for the case of emission by relativistic jets.The approximate formula for the jet-frame size of the emission region, R′ = DcΔtobs, is shown to lead to large systematic errors when used together with observed luminosity and assumed or estimated Doppler ...
openaire +5 more sources
MODELING ACTIVE GALACTIC NUCLEUS FEEDBACK IN COOL-CORE CLUSTERS: THE BALANCE BETWEEN HEATING AND COOLING [PDF]
We study the long-term evolution of an idealized cool-core galaxy cluster under the influence of momentum-driven active galactic nucleus (AGN) feedback using three-dimensional high-resolution (60 pc) adaptive mesh refinement simulations.
Yuan Li, G. Bryan
semanticscholar +1 more source
A Role for the Plastidial GPT2 Translocator in the Modulation of Lignin Biosynthesis
ABSTRACT Engineering plants with reduced lignin content can result in pleiotropic growth defects. In stems of Arabidopsis plants with reduced expression of hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase (HCT), the plastidial glucose 6‐phosphate: phosphate co‐transporter GPT2 is highly overexpressed, and this coincides with reduced lignin ...
Aditi Subramani Raju+4 more
wiley +1 more source
The spin measurement of black holes in active galactic nucleus
Abstract Spin as one of the two parameters describing black holes. Measuring the spin of black holes is very important in black holes research. In this paper, we introduce the method to measure the spin of AGNs which is the X-ray reflection method, including both specific content and precautions.
openaire +2 more sources
SPECTRAL ENERGY DISTRIBUTIONS OF QSOs AT z > 5: COMMON ACTIVE GALACTIC NUCLEUS-HEATED DUST AND OCCASIONALLY STRONG STAR-FORMATION [PDF]
We present spectral energy distributions (SEDs) of 69 QSOs at z > 5, covering a rest frame wavelength range of 0.1 μm to ∼80 μm, and centered on new Spitzer and Herschel observations. The detection rate of the QSOs with Spitzer is very high (97% at λrest
C. Leipski+9 more
semanticscholar +1 more source
Abstract MicroRNAs (miRNAs or miRs) are small, non‐coding RNAs that play a crucial role in gene regulation, making them potential biomarkers for various diseases. In the field of veterinary medicine, there is a growing interest in exploring the diagnostic and therapeutic potential of miRNAs in kidney diseases affecting dogs and cats.
Candice P. Chu, Mary B. Nabity
wiley +1 more source
Dynamical Friction Models for Black Hole Binary Formation in Active Galactic Nucleus Disks
Stellar-mass black holes (sBHs) embedded in gaseous disks of active galactic nuclei (AGN) can be important sources of detectable gravitational radiation for LIGO/Virgo when they form binaries and coalesce due to orbital decay. In this paper, we study the
Kecheng Qian, Jiaru Li, Dong Lai
doaj +1 more source
FROM STARBURST TO QUIESCENCE: TESTING ACTIVE GALACTIC NUCLEUS FEEDBACK IN RAPIDLY QUENCHING POST-STARBURST GALAXIES [PDF]
Post-starbursts are galaxies in transition from the blue cloud to the red sequence. Although they are rare today, integrated over time they may be an important pathway to the red sequence.
Hassen M. Yesuf+7 more
semanticscholar +1 more source
In this paper, an oversimplified model is proposed to test the effects of intrinsic active galactic nucleus (AGN) variability on expected optical quasiperiodic oscillations (QPOs) related to subparsec binary black hole systems (BBHs) in broad-line AGN ...
XueGuang Zhang
doaj +1 more source