Results 101 to 110 of about 4,317,142 (283)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Velocity‐Based‐Training Induces Positive Changes in Muscle Morphology in Parkinson's Disease Patients: A Pilot Study

JCSM Communications
Background High‐speed resistance training has been shown to be a viable intervention for reducing neuromuscular symptoms in older persons with Parkinson's disease.
Caleb P. Calaway, Ana Raquel Calzada, Michel Huyghe, Colten Brown, Humzah Ali, Kylie Martinez, Bryan Mann, Ihtsham Haq, Joseph F. Signorile   +8 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Active management of the third stage of labour in Ethiopia: A systematic review and meta-analysis. [PDF]

PLoS One, 2023
Mihretie GN, Ayele AD, Liyeh TM, Beyene FY, Kassa BG, Arega DT, Belay HG, Worke MD.   +7 more
europepmc   +1 more source

Active Virtual Network Management Prediction: Complexity as a Framework for Prediction, Optimization, and Assurance

, 2002
Research into active networking has provided the incentive to re-visit what has traditionally been classified as distinct properties and characteristics of information transfer such as protocol versus service; at a more fundamental level this paper ...
Bush, Stephen F.
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Pengelolaan Kelas dalam Melaksanakan Pembelajaran Aktif

Ibriez: Jurnal Kependidikan Dasar Islam Berbasis Sains, 2019
Class management is a planned activity that is deliberately carried out by the teacher with the aim of creating and maintaining optimal conditions, building a positive socio-emotional climate and creating a good atmosphere of interpersonal relations.
Siti Muyasaroh
doaj   +1 more source

Practices and factors associated with active management of the third stage of labor in East Africa: systematic review and meta-analysis. [PDF]

BMC Pregnancy Childbirth, 2023
Gelaw KA, Assefa Y, Birhan B, Gebeyehu NA.   +3 more
europepmc   +1 more source

On the Size of the Active Management Industry [PDF]

We argue that active management’s popularity is not puzzling despite the industry’s poor track record. Our explanation features decreasing returns to scale: As the industry’s size increases, every manager’s ability to outperform passive benchmarks ...
Lubos Pastor, Robert F. Stambaugh
core