Results 201 to 210 of about 5,634,404 (299)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Self-sustained frictional cooling in active matter. [PDF]

Nat Commun
Antonov AP, Musacchio M, Löwen H, Caprini L.   +3 more
europepmc   +1 more source

Mind the matter: Active matter, soft robotics, and the making of bio-inspired artificial intelligence. [PDF]

Front Neurorobot, 2022
Harrison D, Rorot W, Laukaityte U.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Metareview: a survey of active matter reviews. [PDF]

Eur Phys J E Soft Matter
Te Vrugt M, Wittkowski R.
europepmc   +1 more source

Computer modeling reveals modalities to actuate mutable, active matter. [PDF]

Nat Commun, 2022
Laskar A, Manna RK, Shklyaev OE, Balazs AC.   +3 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Kadlunga Station. Shropshires at rest [picture] /

, 1891
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11254186 ...
McGann, Terence, active 1891-1900.
core  

The 2025 motile active matter roadmap. [PDF]

J Phys Condens Matter
Gompper G, Stone HA, Kurzthaler C, Saintillan D, Peruani F, Fedosov DA, Auth T, Cottin-Bizonne C, Ybert C, Clément E, Darnige T, Lindner A, Goldstein RE, Liebchen B, Binysh J, Souslov A, Isa L, di Leonardo R, Frangipane G, Gu H, Nelson BJ, Brauns F, Marchetti MC, Cichos F, Heuthe VL, Bechinger C, Korman A, Feinerman O, Cavagna A, Giardina I, Jeckel H, Drescher K.   +31 more
europepmc   +1 more source

Collective pattern formations of animals in active matter physics. [PDF]

Biophys Physicobiol, 2021
Sugi T, Ito H, H Nagai K.
europepmc   +1 more source