Results 51 to 60 of about 3,181,240 (276)

Formulate Adaptive Biphasic Scaffold via Sequential Protein‐Instructed Peptide Co‐Assembly

Advanced Science
To ensure compositional consistency while mitigating potential immunogenicity for stem cell therapy, synthetic scaffolds have emerged as compelling alternatives to native extracellular matrix (ECM).
Yazhou Chen, Qizheng Zhang, Shenyu Yang, Guanying Li, Chaochen Shi, Xunwu Hu, Shunsuke Asahina, Natsuko Asano, Ye Zhang   +8 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Rotaxanes with a photoresponsive macrocycle modulate the lipid bilayers of large and giant unilamellar vesicles

Communications Chemistry
Rotaxanes equipped with actuators hold great potential for developing highly functional molecular machines. Such systems could significantly enhance our ability to study and manipulate biological and artificial membranes.
Udyogi N. K. Conthagamage, Rajitha Rajeshwar T, Stijn van der Ham, Nasim Akhtar, Macallister L. Davis, Senuri G. Jayawardana, Lilia Lopez, Hanumantha Rao Vutukuri, Jeremy C. Smith, Micholas Dean Smith, Víctor García-López   +10 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Spatio-temporal control of the phase separation of chemically active immotile colloids

National Science Open, 2023
Understanding and controlling phase separation in nonequilibrium colloidal systems are of both fundamental and applied importance. In this article, we investigate the spatiotemporal control of phase separation in chemically active immotile colloids.
Peng Yixin, Li Longfei, Guo Shutong, Chen Xi, Zhou Chao, Xing Dingyu, Zhang Hepeng, Yang Mingcheng, Wang Wei   +8 more
doaj   +1 more source

Active Matter Ratchets with an External Drift

, 2013
When active matter particles such as swimming bacteria are placed in an asymmetric array of funnels, it has been shown that a ratchet effect can occur even in the absence of an external drive. Here we examine active ratchets for two dimensional arrays of
Reichhardt, C., Reichhardt, C. J. Olson
core   +1 more source

High-energy neutrino conversion and the lepton asymmetry in the universe [PDF]

, 2001
We study matter effects on oscillations of high-energy neutrinos in the Universe. Substantial effect can be produced by scattering of the neutrinos from cosmological sources ($z\gta 1$) on the relic neutrino background, provided that the latter has large
A. Abbasabadi, A. Abbasabadi, A. Balbi, A. E. Lange, A. Yu. Smirnov, C. Lunardini, C. Lunardini, D. A. Dicus, D. A. Dicus, D. Fargion, D. Notzold, D. W. Hogg, E. Roulet, E. Waxman, E. Waxman, F. Halzen, F. W. Stecker, G. B. Larsen, G. G. Raffelt, G. Gelmini, G. Gelmini, G. Raffelt, G. Sigl, H. Athar, H. Athar, H. Athar, H. J. M. S. Mao, H. Kang, J. Alvarez-Muniz, J. G. Learned, J. J. Blanco-Pillado, J. L. Crooks, J. Lesgourgues, J. Lesgourgues, J. N. Bahcall, J. Pantaleone, J. Pantaleone, K. Enqvist, L. Bento, L. Stodolsky, M. C. Gonzalez-Garcia, M. J. S. Levine, M. Krumholz, M. Schmidt, P. Bhattacharjee, P. Bhattacharjee, P. Bhattacharjee, P. de Bernardis, R. J. Protheroe, S. Dodelson, S. Esposito, S. Esposito, S. Hanany, S. Hannestad, S. I. Dutta, S. Samuel, S. Samuel, T. J. Weiler, V. A. Kostelecky, V. A. Kostelecky, V. A. Kostelecky, V. A. Kostelecky, V. K. Cung, W. H. Kinney, X. Shi   +64 more
core   +2 more sources

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Nature’s engines: active matter [PDF]

Europhysics News, 2017
Active materials, bacteria, molecular motors, and self-propelled colloids, continuously transform chemical energy from the environment to mechanical work. Dense active matter, from layers of cells to flocks of birds, self-assembles into intricate patterns.
openaire   +3 more sources

Neutrino self-polarization effect in matter

, 2004
The quasi-classical theory of the spin light of neutrino ($SL\nu$) in background matter, accounting for the neutrino polarization, is developed. The neutrino transitions $\nu_{L}\to \nu_{R}$ and $\nu_{R}\to \nu_{L}$ rates in matter are calculated.
Alexander Studenikin, Andrey Lobanov, Bargmann, Bernabéu, Bilenky, Borisov, Dvornikov, Dvornikov, Dvornikov, Dvornikov, Egorov, Egorov, Fujikawa, Fujikawa, Ioannisian, Lobanov, Lobanov, Lobanov, Studenikin, Studenikin   +19 more
core   +1 more source