Results 41 to 50 of about 7,204,380 (286)

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Intergenerational active play: a scoping review

Proceedings of the 34th Australian Conference on Human-Computer Interaction, 2022
This paper presents a scoping review of intergenerational active play to provide an overview of current research in HCI and related disciplines. Play has been widely perceived as a common activity among people of all ages. Physical activity and active play are essential to positive developmental outcomes, especially of those in preschool years ...
Khoa-Dang Tran, Alethea Blackler, Bernd Ploderer, Nicole E. M. Vickery   +3 more
openaire   +2 more sources

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Position Statement on Active Outdoor Play [PDF]

International Journal of Environmental Research and Public Health, 2015
A diverse, cross-sectorial group of partners, stakeholders and researchers, collaborated to develop an evidence-informed Position Statement on active outdoor play for children aged 3–12 years. The Position Statement was created in response to practitioner, academic, legal, insurance and public debate, dialogue and disagreement on the relative benefits ...
Tremblay, Mark S., Gray, Casey, Babcock, Shawna, Barnes, Joel, Bradstreet, Christa Costas, Carr, Dawn, Chabot, Guylaine, Choquette, Louise, Chorney, David, Collyer, Cam, Herrington, Susan, Janson, Katherine, Janssen, Ian, Larouche, Richard, Pickett, William, Power, Marlene, Sandseter, Ellen Beate Hansen, Simon, Brenda, Brussoni, Mariana   +18 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Coincident play: temporal and spatial overlaps of play activities

Culture, Theory and Critique, 2021
Previous research successfully addresses how digital play fits into the social relations of urban space, often disrupting or enriching them (e.g., Montola [2005]. ‘Exploring de Edge of the Magic Circle: Defining Pervasive Games’. Proceedings of the Digital Arts and Culture 2005 Conference.
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The power of play: Innovations in Getting Active Summit 2011: a science panel proceedings report from the American Heart Association

, 2011
To examine the influence active-play video gaming (also referred to as exergaming, exertainment, and active gaming) might have on improving health-related skills, enhancing self-esteem and self-efficacy, promoting social support, and ultimately ...
Vafiadis, Dorothea K, Chamberlin, Barbara, Power of Play: Innovations in Getting Active Summit Planning Committee, Medina, Jr, Ernie, Franklin, Barry A, Lieberman, Debra A, Sanner, Brigid McHugh   +6 more
core   +2 more sources