Results 101 to 110 of about 348,539 (265)

Coupled Active Shape Models for Automated Segmentation and Landmark Localization in High-Resolution CT of the Foot and Ankle. [PDF]

Proc SPIE Int Soc Opt Eng, 2019
Brehler M, Islam A, Vogelsang L, Yang D, Sehnert W, Shakoor D, Demehri S, Siewerdsen JH, Zbijewski W.   +8 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Abdomen and spinal cord segmentation with augmented active shape models. [PDF]

J Med Imaging (Bellingham), 2016
Xu Z, Conrad BN, Baucom RB, Smith SA, Poulose BK, Landman BA.   +5 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Automatic lung segmentation in functional SPECT images using active shape models trained on reference lung shapes from CT. [PDF]

Ann Nucl Med, 2018
Cheimariotis GA, Al-Mashat M, Haris K, Aletras AH, Jögi J, Bajc M, Maglaveras N, Heiberg E.   +7 more
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Texture Analysis of T2-Weighted Images as Reliable Biomarker of Chronic Kidney Disease Microstructural State

Biomedicines
Objectives: The diagnostics of chronic kidney disease (CKD) consist of three basic groups of examinations: laboratory tests, radiological imaging and histopathological examinations.
Marcin Majos, Artur Klepaczko, Katarzyna Szychowska, Ludomir Stefanczyk, Ilona Kurnatowska   +4 more
doaj   +1 more source

Whole Abdominal Wall Segmentation using Augmented Active Shape Models (AASM) with Multi-Atlas Label Fusion and Level Set. [PDF]

Proc SPIE Int Soc Opt Eng, 2016
Xu Z, Baucom RB, Abramson RG, Poulose BK, Landman BA.   +4 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Spike structure of gold nanobranches induces hepatotoxicity in mouse hepatocyte organoid models

Journal of Nanobiotechnology
Background Gold nanoparticles (GNPs) have been extensively recognized as an active candidate for a large variety of biomedical applications. However, the clinical conversion of specific types of GNPs has been hindered due to their potential liver ...
Rui Zhang, Dan Li, Ruibo Zhao, Dandan Luo, Yeting Hu, Shengyan Wang, Xiaolu Zhuo, M. Zubair Iqbal, Han Zhang, Qianqian Han, Xiangdong Kong   +10 more
doaj   +1 more source