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The nature of the active site of hemerythrin
Archives of Biochemistry and Biophysics, 1957Abstract The oxygen-carrying pigment, hemerythrin, contains 0.81% Fe and has 2.4 Fe atoms per O2 molecule bound. It has been demonstrated that 2 of the 2.4 iron atoms are bound directly to the protein through sulfhydryl side chains, and that these two are close neighbors.
Irving M. Klotz+5 more
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Superfamily active site templates
Proteins: Structure, Function, and Bioinformatics, 2004AbstractWe show that three‐dimensional signatures consisting of only a few functionally important residues can be diagnostic of membership in superfamilies of enzymes. Using the enolase superfamily as a model system, we demonstrate that such a signature, or template, can identify superfamily members in structural databases with high sensitivity and ...
Benjamin J. Polacco+2 more
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Seminars in Thrombosis and Hemostasis, 1986
Knowledge is being gained about topographic features of alpha-thrombin and how they may define thrombin specificity and biologic functions. Thrombin is not just an enzyme with moderately restricted proteolytic capabilities, yet with extraordinarily high specificities for certain bonds (such as the A alpha-cleavage site in fibrinogen), but also is a ...
John W. Fenton, David H. Bing
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Knowledge is being gained about topographic features of alpha-thrombin and how they may define thrombin specificity and biologic functions. Thrombin is not just an enzyme with moderately restricted proteolytic capabilities, yet with extraordinarily high specificities for certain bonds (such as the A alpha-cleavage site in fibrinogen), but also is a ...
John W. Fenton, David H. Bing
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Active site peptides of rhodanese
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1970Abstract The active site cysteinyl peptide isolated from a tryptic digest of rhodanese (thiosulfate:cyanide sulfurtransferase, EC 2.8.1.1) by column chromatography has been found to contain 15 amino acid residues, of which 7 are hydrophobic. The tryptophyl peptides in such digests also appear to consist predominantly of residues which are hydrophobic.
John Westley, Francis DeToma
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Angewandte Chemie, 2017
An active and stable photocatalyst to directly split water is desirable for solar-energy conversion. However, it is difficult to accomplish overall water splitting without sacrificial electron donors.
Wei Liu+12 more
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An active and stable photocatalyst to directly split water is desirable for solar-energy conversion. However, it is difficult to accomplish overall water splitting without sacrificial electron donors.
Wei Liu+12 more
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On the nature of “SERS active sites”
Surface Science Letters, 1985Abstract Active sites of short range enhancement in surface enhanced Raman scattering (SERS) of adsorbates on cold deposited, porous silver films have been envisioned either as “cavity sites with local electromagnetic resonances” or as “sites of atomic scale roughness with photon driven charge transfer between metal and adsorbate”. Whereas SERS of CO
Ü. Ertürk+3 more
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Ticrynafen: Site of Natriuretic Activity
Nephron, 1979Studies were performed with ticrynafen (tienilic acid) to determine its natriuretic site of action, detailed electrolyte excretion, and its effect on acid excretion and bicarbonate reabsorption. With 500 and 1,000 mg oral doses under conditions of water diuresis, there was a decrease in free water excretion as osmolar clearance increased.
R.G. Familiar+5 more
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Nanoparticle Surface as Activation Site
Journal of Nanoscience and Nanotechnology, 2010The immense surface-to-volume (S/V) ratio in nanoparticles leads to large surface energy density. These high densities play the role of sites for activities that are not triggered in bulk materials. Here we present some examples of such distinctive activities taking place at nanoparticle surfaces. Our first example involves the morphological changes in
Nupur Biswas+4 more
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, 2014
We present a series of perovskite electrocatalysts that are highly active for both the oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) in an aqueous alkaline electrolyte.
William G. Hardin+9 more
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We present a series of perovskite electrocatalysts that are highly active for both the oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) in an aqueous alkaline electrolyte.
William G. Hardin+9 more
semanticscholar +1 more source
1985
Monoclonal antibodies (MAbs) have provided powerful new tools for analysis of enzyme function. MAbs directed at specific subsites of the enzyme active site allow analysis of catalysis at a new level of resolution even for relatively simple, monomeric enzymes.
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Monoclonal antibodies (MAbs) have provided powerful new tools for analysis of enzyme function. MAbs directed at specific subsites of the enzyme active site allow analysis of catalysis at a new level of resolution even for relatively simple, monomeric enzymes.
openaire +2 more sources