Results 221 to 230 of about 8,153,669 (282)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A decadal profile of RhD-negative blood donors in Chongqing, China: demographics, phenotypic diversity, and donation behavior. [PDF]

Front Public Health
Gan Y, Xie C, Liu B, Chen H, Qin W.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Dissecting Sense of Agency in Schizophrenia: A Predictive Coding Perspective. [PDF]

Schizophr Bull
Rossetti I, Musco MA, Sacheli LM, Capuzzi E, Clerici M, Caldiroli A, Demartini B, Broglia G, Nisticò V, Florio V, Conca A, Maravita A, Paulesu E, Zapparoli L.   +13 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Quantum-classical hybrid computation of electron transfer in a cryptochrome protein <i>via</i> VQE-PDFT and multiscale modeling. [PDF]

Chem Sci
Chen Y, Sheng Z, Li W, Zhang Y, Xu X, Huang JH, Li Y.   +6 more
europepmc   +1 more source

Energy-efficient architecture for perception layer of IoT system. [PDF]

Sci Rep
Kamaludin KH, Ismail W.
europepmc   +1 more source

Adaptive virtual impedance control strategy based on IWOA-fuzzy PID and its application to reactive power sharing in islanded microgrids. [PDF]

Sci Rep
Hou Y.
europepmc   +1 more source

Temporary Pacing with Active-Fixation Leads: Clinical and Economic Impact Versus Conventional Temporary Transvenous Pacing. [PDF]

J Clin Med
Vicente-Miralles R, Rivas-Gándara N, Antón Pascual JL, Adeliño R, Ajo Ferrer R, Núñez Martínez JM, Solera Suárez M, Ibáñez Criado A, García-Fernández A, Ruiz Nodar JM, Bertomeu-Gonzalez V, Martínez Martínez JG.   +11 more
europepmc   +1 more source

Prostate Cancer Disparities Between Public and Private Healthcare Patients in Tasmania, a Regional State of Australia. [PDF]

Cancers (Basel)
Foley GR, Blizzard CL, Skala M, Redwig F, Roydhouse J, Dickinson JL, FitzGerald LM.   +6 more
europepmc   +1 more source