Results 91 to 100 of about 4,685,441 (360)

Females and Tourism Activities: An Insight for All-female Tours in Hong Kong [PDF]

open access: yesJournal of China Tourism Research, 2017
Although all-female tours have become popular in Western and Asian countries, until now researchers have not paid much attention to this niche but important market. This study aims to explore female tourists’ desired activities towards an ‘all-female activity-based outbound tour’ in Hong Kong. A survey was administered to tourists who joined short- and
openaire   +2 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

An On-Campus Botanical Tour to Promote Student Satisfaction and Learning in a University Level Biodiversity or General Biology Course

open access: yesEducation Sciences, 2017
Outdoor, hands-on and experiential learning, as opposed to instruction-based learning in classroom, increases student satisfaction and motivation leading to a deeper understanding of the subject.
Harish H. Ratnayaka
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

KOMUNIKASI INTERNAL ORGANISASI MELALUI VIDEO PROFILE (Studi pada Karyawan PT. Mukti Usaha Maju (MUM) Travel Organizer) [PDF]

open access: yes, 2006
The ability of communication impacts to someone’s success in transmitting messages clearly, humanly, and efficiently. This manifests through the message decoding accurately.
Yudhistira, Yudha
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

A Copula-Based Joint Model of Commute Mode Choice and Number of Non-Work Stops during the Commute [PDF]

open access: yes, 2011
At the time of publication A. Portoghese, E. Spissu, and I. Meloni were at University of Cagliari, and C.R. Bhat and N. Eluru were at the University of Texas at Austin.In this paper, in the spirit of a tour-based frame of analysis, we examine the commute
Portoghese, Alessandro   +4 more
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Long-term responses of Burrunan dolphins (Tursiops australis) to swim-with dolphin tourism in Port Phillip Bay, Victoria, Australia: A population at risk

open access: yesGlobal Ecology and Conservation, 2014
This study investigated Burrunan dolphin responses to dolphin-swim tour vessels across two time periods: 1998–2000 and 2011–2013. A total of 211 dolphin sightings were documented across 306 surveys.
Nicole E. Filby   +2 more
doaj  

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