Results 121 to 130 of about 601,728 (351)
La mythanalyse comme grille de lecture
M@GM@, 2018 Ce texte a pour unique ambition d'aborder les principaux points qui seraient à étudier pour déterminer en quoi la mythanalyse, définie comme : une tentative « de repérer et de déchiffrer les mythes qui déterminent les imaginaires sociaux d'aujourd'hui […]
Lorenzo Soccavo
doaj
Sublime encounters: Commodifying the experience of the geos
Geo: Geography and Environment, 2018 This paper discusses the rise in volcano tourism in the last few decades, focusing on its impact in recent eruptive crises in Iceland. The paper uses evidence from ethnographic research and surveys to argue that two divergent economic narratives come ...
Amy Donovan
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Clay mineralogy of tephras and associated paleosols and soils, and hydrothermal deposits, North Island [New Zealand] [PDF]
, 1993 Tour themes and itinerary The tour centres on the occurrence and genesis of clay minerals, especially allophane, halloysite, and ferrihydrite, associated with both Quaternary rhyolitic airfall tephra (volcanic ash) deposits and volcanogenic alluvium ...
Lowe, David J., Percival, H.J.
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Clean Clothes national campaigns and projects: June to October 2005 [PDF]
, 2005 A compilation of country reports on the activities of the various European Clean Clothes Campaigns from June to October ...
Clean Clothes Campaign
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Journal of Information Systems and InformaticsThis research evaluates user satisfaction with the e-administration system at the Village-Owned Enterprises (BUMDes) Melung, focusing on identifying features that influence user satisfaction using the Kano model.
Ilham Albana +2 more
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source