Results 181 to 190 of about 2,374,890 (276)

Human ferroportin mediates proton-coupled active transport of iron. [PDF]

Blood Adv, 2020
Li S, Yang Y, Li W.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Reliability assessment of the 'field audit for children's active transport routes to school' (FACTS) tool. [PDF]

BMC Public Health
Vasey TV, Dale MJ, Carroll SJ.
europepmc   +1 more source

Is the physical activity environment surrounding primary schools associated with students' weight status, physical activity or active transport, in regional areas of Victoria, Australia? A cross-sectional study. [PDF]

BMJ Open, 2021
Jacobs J, Crooks N, Allender S, Strugnell C, Backholer K, Nichols M.   +5 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Hydrodynamic Fluidic Pump Empowered Sensitive Recognition and Active Transport of Hydrogen Peroxide in 1D Channels. [PDF]

Adv Sci (Weinh)
Liu S, Guo Y, Gong Y, Wei Y, Hu Q, Yu L.
europepmc   +1 more source

What Is the Best Practice Method for Quantifying the Health and Economic Benefits of Active Transport? [PDF]

Int J Environ Res Public Health, 2020
Möller H, Haigh F, Hayek R, Veerman L.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Seamounts generate efficient active transport loops to nourish the twilight ecosystem. [PDF]

Sci Adv
Wang X, Li H, Zhang J, Chen J, Xie X, Xie W, Yin K, Zhang D, Ruiz-Pino D, Kao SJ.   +9 more
europepmc   +1 more source

The HSV1 Tail-Anchored Membrane Protein pUL34 Contains a Basic Motif That Supports Active Transport to the Inner Nuclear Membrane Prior to Formation of the Nuclear Egress Complex. [PDF]

Viruses, 2021
Funk C, Marques da Silveira E Santos D, Ott M, Raschbichler V, Bailer SM.   +4 more
europepmc   +1 more source