Results 91 to 100 of about 3,874,422 (291)
Utility Cycling – Experiences Within a Disabled Family Group
Cycling is associated with a range of well-established positive effects, from personal physical and mental health improvements to financial, environmental, social and logistical benefits.Disabled people are under-represented in cycling and especially ...
Kate Ball
doaj +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Newsletter dedicated to traveling in Texas, including information about news, locations, and events of interest to visitors as well as statistics and summaries of travel in the ...
Texas. Travel and Information Division.
core +1 more source
Inclusive Cycling in North East Scotland
Grampian Inclusive Cycling Bothies (GICB) is a partnership led by Grampian Disability Sport and Sport Aberdeen with the aim of supporting access to inclusive cycling throughout the North East of Scotland.
Caroline Hood
doaj +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Cycling helped me embrace my disabled identity
Using a bike as a mobility aid was not a conscious decision, but it is how I began to understand that I am disabled, and that disability is a fundamental part of my identity.
Jillian Chalmers Banfield
doaj +2 more sources
ICC Cricket World Cup 2007 Travel Arrangements
Travel arrangements for Dr and Mrs Uren in the West Indies for the ICC Cricket World Cup as provided by EduSport ...
EduSport Travel
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source

