Results 61 to 70 of about 3,874,422 (291)

Is Canada’s commuter bicycling population becoming more representative of the general population over time? A national portrait of bicycle commute mode share 1996–2016.

open access: yesActive Travel Studies, 2023
Despite equity gaining increasing attention in Canadian bicycling practice and research, the demographics of who is bicycling have not been documented nationally in Canada.
Carly MacEacheron   +5 more
doaj   +2 more sources

Extending activity-based models of travel demand to represent activity-travel behaviour of children: some descriptive results [PDF]

open access: yesWIT Transactions on The Built Environment, 2008
This paper reports some descriptive findings of activity-travel behaviour of children. Summary statistics are compared with those pertaining to household heads. Significant differences are found between children and household heads on virtually all indicators. It suggests that activity-based models of transport demand need to systematically include the
Arentze, T., Timmermans, H.
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Transforming Disability Through Cycling: Learning to Ride as an Adult with Cerebral Palsy

open access: yesActive Travel Studies
This article details my experience of learning to ride an adapted trike as an adult. Using a bike has transformed my life in so many ways, but perhaps surprisingly, the benefits are more around empowerment and mental wellbeing than improved fitness ...
Finn Daniel Francis O'Keefe
doaj   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Increasing the Visibility of Invisibly Disabled Cyclists: A Personal Account from a Deaf Cyclist

open access: yesActive Travel Studies
Visibility and representation are necessary factors in supporting Disabled people’s access to cycling. The visibility of Disabled cyclists in policy, such as images of non-standard cycles, is paramount to ensuring Disabled cyclists are considered in ...
Florence Grieve
doaj   +2 more sources

Governance, human agency and other blindspots in active transport practice — and research

open access: yesActive Travel Studies, 2022
At the root of the multiple, diverse and multi-scalar challenges facing the living systems we call cities likes a single enormous knot: figuring out how to live together very differently, in light of climate crisis, pandemics, loss of biodiversity and ...
Lake Sagaris
doaj   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Is active travel associated with greater physical activity? The contribution of commuting and non-commuting active travel to total physical activity in adults

open access: yesPreventive Medicine, 2012
To complement findings that active travel reduces the risk of morbidity and mortality from chronic diseases, an understanding of the mechanisms through which active travel may lead to improved health is required.The aim of this study is to examine the descriptive epidemiology of all active travel and its associations with recreational and total ...
Sahlqvist, Shannon   +2 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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