Results 41 to 50 of about 3,426,135 (243)

Assessment of Strong Earthquake Risk in Maqin–Maqu Segment of the Eastern Kunlun Fault, Northeast Tibet Plateau

open access: yesApplied Sciences
The East Kunlun Fault Zone, as a highly seismically active fault, has witnessed five earthquakes with magnitudes exceeding M7.0 to the west of Animaqing Mountain since 1900.
Zhengfang Li, Bengang Zhou
doaj   +1 more source

Erosion Associated with Seismically-Induced Landslides in the Middle Longmen Shan Region, Eastern Tibetan Plateau, China

open access: yesRemote Sensing, 2017
The 2008 Wenchuan earthquake and associated co-seismic landslide was the most recent expression of the rapid deformation and erosion occurring in the eastern Tibetan Plateau.
Zhikun Ren, Zhuqi Zhang, Jinhui Yin
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Coupled subdaily and multiweek cycles during the lava dome eruption of Soufriere Hills Volcano, Montserrat [PDF]

open access: yes, 2013
Observations of volcanoes extruding andesitic lava to produce lava domes often reveal cyclic behaviour. At Soufriere Hills Volcano, Montserrat, cycles with sub-daily and multi-week periods have been recognised on many occasions.
Costa, A.   +12 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Investigating potential icequakes at Llaima volcano, Chile

open access: yesVolcanica, 2020
Glacially- and magmatically-derived seismic events have been noted to heavily overlap in characteristics, thus there exists the potential for false-alarms or missed warnings at ice-covered volcanoes. Here we present the first study to specifically target
Oliver Lamb   +6 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

The brittle-ductile transition in active volcanoes [PDF]

open access: yesScientific Reports, 2019
AbstractContrasting deformation mechanisms precede volcanic eruptions and control precursory signals. Density increase and high uplifts consistent with magma intrusion and pressurization are in contrast with dilatant responses and reduced surface uplifts observed before eruptions.
Francesco Parisio   +3 more
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The Activity of the Yaziba Fault on the Lower Reaches of the Jinsha River, Southwestern China: Indirect Evidence from Paleo Earthquakes and Ancient Landslides

open access: yesAdvances in Civil Engineering, 2019
In this paper, in order to confirm the strong activity of the Yaziba Fault and provide information needed for disaster prevention and mitigation and safety of the reservoir, we use field investigations and remote sensing interpretations to obtain the ...
Yulong Cui, Jianhui Deng, Chong Xu
doaj   +1 more source

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