Results 71 to 80 of about 3,426,135 (243)
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Monitoring volcanoes is a surprisingly controversial enterprise. Some volcanologists argue that monitoring promises too much and delivers too little for risk mitigation. They trust only strict land‐use measures (and accompanying high insurance premiums in risky zones) and urge that funds be used for public education and awareness rather than for ...
openaire +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Thermal remote sensing is currently an emerging technique for monitoring active volcanoes around the world. The study area, the Aso volcano, is currently the most active and has erupted almost every year since 2012.
Md. Bodruddoza Mia +2 more
doaj +1 more source
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
Determining the stress field in active volcanoes using focal mechanisms
Stress inversion of seismological datasets became an essential tool to retrieve the stress field of active tectonics and volcanic areas. In particular, in volcanic areas, it is able to put constrains on volcano-tectonics and in general in a better ...
Bruno Massa +5 more
doaj +1 more source
Endothelial Cell Proteins as Biomarkers in Susac Syndrome
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin +11 more
wiley +1 more source
RRS "Charles Darwin" Cruise 178, 14 Mar - 11 Apr 2006. 3D seismic acquisition over mud volcanoes in the Gulf of Cadiz and submarine landslides in the Eivissa Channel, western Mediterranean Sea [PDF]
The major aims of Charles Darwin Cruise 178 were to obtain (i) 3D seismic imagery, video transects and swath bathymetry maps of mud volcanoes in the southern Gulf of Cadiz, (ii) video transects across suspected cold water coral reefs in the Alboran Sea ...
Berndt, C., Masson, D.G.
core +1 more source
PCGF1 Promotes the Tumorigenesis of Malignancies Through Upregulating CCDC34 in Glioma
ABSTRACT Background Polycomb group factor 1 (PCGF1) and coiled‐coil domain‐containing protein 34 (CCDC34) have been implicated in tumorigenesis in multiple malignancies. However, their biological functions and prognostic significance in glioma remain poorly defined.
Yuanbing Chen +7 more
wiley +1 more source

