Results 61 to 70 of about 14,136,893 (299)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

BES1 is activated by EMS1-TPD1-SERK1/2-mediated signaling to control tapetum development in Arabidopsis thaliana

open access: yesNature Communications, 2019
BES1 and BZR1 transcription factors are activated by the BRI1-BAK1 receptor complex during brassinosteroid signaling. Here the authors show that BES1-family members also act in anthers, downstream of another receptor-like kinase-mediated signaling ...
Weiyue Chen   +8 more
doaj   +1 more source

Temperature VS Carbon Dioxide [PDF]

open access: yes
In this activity, students examine the relationship between carbon dioxide levels and global temperature change by studying a graph of these two variables.

core  

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Characteristics of the Artistic Construction of Light and Color Focus in the Theater Performance

open access: yesالاكاديمي, 2019
The theater has a living environment that resembles or realistically simulates the real life environment on the stage where we see the place, light and living being  as elements representing a picture of the life scene and for a period of time the ...
Mohamed Aziz Hassan
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Plate Tectonics: Earthquake Epicenter [PDF]

open access: yes
This lesson provides an overview of destructive earthquakes and their connection to tectonic movements of the Earth's crust. It includes a discussion of some especially destructive historic earthquakes, and a brief introduction to contintental drift and ...
John Pratte
core  

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Food Calories and Land [PDF]

open access: yes
Obesity is on the rise in the United States, due primarily to the size and composition of the American diet. Discussion topics include lack of exercise, changes in calorie intake over time, and environmental impacts of these increases in consumption ...
John Pratte
core  

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