Results 131 to 140 of about 110,078 (271)

The AMR footprint: an integrative indicator in the global response to antimicrobial resistance. [PDF]

JAC Antimicrob Resist
Essack SY.
europepmc   +1 more source

Recognitions of Special Teachers on Support Plan and Execution of Topic Selection Activities in Special School Free Semester

Journal of Special Education for Curriculum and Instruction, 2018
null 유장순, null Lee okin, null 고혜정, null Kim, Dae Ryong   +3 more
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

crRNA scaffold remodeling controls CRISPR-Cas12a activity for enhanced performance. [PDF]

Nucleic Acids Res
Wang Z, Wu Y, Wang Z, Zhang S, Liu H, Nie Y, Chen K, Huang Y, Zhou Y, Cao Y, Sun L, Hao R.   +11 more
europepmc   +1 more source

The IPCHEM Platform: Main Tools and Functionalities, Data Integration Status, On-Going and Planned Activities, Impact and Recognition

ISEE Conference Abstracts, 2018
Silvia Dalla Costa, Stylianos Kephalopoulos   +1 more
openaire   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Disruption of <i>TcGNBP3</i> via RNA interference compromises antibacterial immunity in <i>Tribolium castaneum</i>. [PDF]

Virulence
Bi J, Li Q, Liu P, Li J, Gao R, Zhao T, Yuan X, Hao H, Wang Y, Li B.   +9 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Potential of Vγ9Vδ2T cells in tuberculosis: integration of innate and adaptive immunity for vaccine development. [PDF]

PeerJ
Di D, Gao C, Deng Y, Li Y, Zhang Y.
europepmc   +1 more source

THE EFFECTS OF CARE LEVEL 3 ELDERLY PEOPLE AND THEIR SELF RECOGNITION TO LIVING ACTIVITIES THROUGH THE HOUSING REPAIRS(Architectural Planning and Design)

AIJ Journal of Technology and Design, 2006
Tetuyuki SASAKI, Kazutaka KUROSAWA
openaire   +2 more sources