Results 31 to 40 of about 110,078 (271)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Analytic Decision Gaming: A Tool for Crisis Response and Clinical Reasoning

open access: yesJournal of Regional Medical Campuses, 2021
Issue:  Medical education traditionally focuses on basic science during the first two years of medical school. To “flip” this model, the Penn State College of Medicine has introduced and inquiry-based educational strategy that introduces students to the ...
Morgan Decker   +2 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Unsupervised Machine Learning for Developing Personalised Behaviour Models Using Activity Data

open access: yesSensors, 2017
The goal of this study is to address two major issues that undermine the large scale deployment of smart home sensing solutions in people’s homes. These include the costs associated with having to install and maintain a large number of sensors, and the ...
Laura Fiorini   +4 more
doaj   +1 more source

Activity of a member of the Tambov Governorate Zemstvo Board A.D. Bryukhatov (1898–1904) in the context of the formation of civil society in Russia

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2023
Importance. The history of zemstvo autonomy in the all Russian plan has been studied extensively. The contribution to the history of prominent representatives of the zemstvo has been studied much less on local, in particular, Tambov material. The purpose
D. A. Shuvaev
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reduce Cost Smart Power Management System by Utilize Single Board Computer Artificial Neural Networks for Smart Systems

open access: yesInternational Journal of Computational Intelligence Systems, 2019
The plan and usage of a smart power management system for household and buildings that control numerous electrical appliances in real time have been reported in this work.
Sudad J. Ashaj, Ergun Erçelebi
doaj   +1 more source

How Often Are We in the Here and Now?

open access: yesSocial Sciences, 2023
There is a conflict between humans’ need to focus on the present circumstances and their ability to plan and reminisce, which often results in mind wandering.
Şerban Procheş
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

EXPERIMENTAL SIMULATION OF POST-OPERATIVE COGNITIVE DISORDERS IN RATS

open access: yesВестник анестезиологии и реаниматологии, 2018
Goal: to develop the design of the experiment for evaluation of cognitive functions and behavior of rats after some aggressive impact imitating anesthesia and surgery in the clinical practice.
I. V. Belozertseva   +4 more
doaj   +1 more source

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