Results 91 to 100 of about 185,168 (287)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Evaluation of the cost price of conventional laboratory services in the selected hospital of Tehran University of Medical Sciences and its comparison with the tariffs approved by the Ministry of Health and Medical Education in 2019

open access: yesبیمارستان, 2020
Background: Considering the importance and position of the health sector in socio-economic development programs, it is necessary to be aware of the current situation and to recognize its issues and problems.
Hojjat Rahmani   +4 more
doaj  

PENGARUH ACTIVITY BASED COSTING SYSTEM (ABC SYSTEM) TERHADAP KINERJA PERUSAHAAN DAN DAMPAKNYA PADA KEUNGGULAN BERSAING (Studi Pada PT Bio Farma) [PDF]

open access: yes, 2017
ABSTRAK Penelitian ini bertujuan untuk meneliti secara empiris mengenai pengaruh activity based costing system terhadap kinerja perusahaan dan dampaknya pada keunggulan bersaing pada perusahaan Bio Farma (Persero).
WIWIN CAHYANI, 134020256
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

An exploration of the factors affecting the diffusion of Advanced Costing techniques: a comparative analysis of two surveys (1996-2005) [PDF]

open access: yes
The issue of cost calculation has been largely debated in the last years under the pressure of the perceived lost of relevance of the so called "traditional cost accounting approaches".
Cinquini, Lino   +3 more
core   +4 more sources

Determine of cost drivers in Activity Based Costing method of hospital services

open access: yesپژوهش‌های سلامت‌محور, 2019
Determination of Cost Drivers through Activity Based Costing Method in Determination of Hospital Services Costs  Meshkani Zahra1, Reza Pour Aziz2, Alipour Vahid3, Farabi Hero1*, Mazdaki Alireza4, Hakimi Narges5 1. Ph.D.
Zahra Meshkani   +5 more
doaj  

EFFECTIVE COST ANALYSIS TOOLS OF THE ACTIVITY-BASED COSTING (ABC) METHOD [PDF]

open access: yes
This article focuses on cost analysis and specific tools of Activity-Based Costing(ABC) method. After presenting the main categories of operating costs of ABC method it isswitching to presenting the most important tools for monitoring and measuring ...
Sorin Briciu, Sorinel Capusneanu
core  

PENENTUAN HARGA POKOK TARIF KAMAR HOTEL MENGGUNAKAN METODE ACTIVITY-BASED COSTING SYSTEM SEBAGAI PENDEKATAN BARU PADA HOTEL SEGORO JEPARA [PDF]

open access: yes, 2015
Metode Activity-Based Costing System adalah sebuah metode yang menerapkan konsep akuntansi biaya untuk menentukan harga dengan lebih akurat. Penelitian ini bertujuan untuk mengetahui perbedaan perhitungan harga pokok tarif kamar hotel dengan menggunakan ...
PARAMITA, INDRASWARI
core  

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