Results 91 to 100 of about 1,625,987 (302)

FOOTPRINT AND DIRECT IMPACT OF ANTHROPOGENIC ACTIVITIES ON GROUNDWATERS FROM MEDIAS AREA

open access: yesStudia Universitatis Babes-Bolyai Chemia, 2015
Groundwater represents an important and direct source of fresh water, vulnerable to contamination. Groundwater composition is easily influenced by anthropogenic activities. Lack of sewerage facilities impress direct footprint on groundwater composition.
Maria-Alexandra HOAGHIA   +3 more
doaj  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Quasi-Critical Brain Dynamics on a Non-Equilibrium Widom Line

open access: yes, 2014
Is the brain really operating at a critical point? We study the non-equilibrium properties of a neural network which models the dynamics of the neocortex and argue for optimal quasi-critical dynamics on the Widom line where the correlation length is ...
Beggs, John M.   +3 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Exact solution of the one-dimensional deterministic Fixed-Energy Sandpile

open access: yes, 2006
In reason of the strongly non-ergodic dynamical behavior, universality properties of deterministic Fixed-Energy Sandpiles are still an open and debated issue.
A. Bjorner   +4 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

ANALISIS RISIKO OPERASIONAL PADA PT. INDONESIA NIHON SEIMA [PDF]

open access: yes, 2009
ANALISIS RISIKO OPERASIONAL PADA PT. INDONESIA NIHON SEIMA - Lokasi Kantor, Tata Letak Kantor, Metode Pemeringkatan Faktor, Activity Relationship Chart, Activity Relationship ...
FARETHA, RIZTYA
core  

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