Results 181 to 190 of about 659,826 (317)

Enhancing social participation in older adults with noncommunicable diseases: insights from system dynamics modeling. [PDF]

BMC Public Health
Liu C, Hu B, Wang Y, Pang X, Guo K, Zhu X.   +5 more
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

CircRNA CeRNA networks in gastric cancer highlight FAP/FNDC1 as potential prognostic and therapeutic targets. [PDF]

Discov Oncol
Yu J, Yin LK, Li Q, Li M, Qin XZ, Gong L, Qin L, Tian YH, Lv ZB, Wang P.   +9 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Research on the potential mechanisms of propofol in treating depression after brain injury based on network pharmacology. [PDF]

Medicine (Baltimore)
Ma FT, Xie BH, Xiao QX, Xiong LL, Liu F.
europepmc   +1 more source

Model Decomposition of Robustness Diagram with Loop and Time Controls to Sequence Diagrams Using Activity Groups [PDF]

Kliezl P. Eclipse, Jasmine A. Malinao
openalex   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Extending Modelling Activity Diagrams as a tool to characterise mathematical modelling processes

, 2019
Lluís Albarracín, Jonas Bergman Ärlebäck, Elisabeth Civil, Núria Gorgorió   +3 more
openalex   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Structure-effect relationship of phenolic compounds on <i>α</i>-amylase inhibition studied by isothermal titration calorimetry. [PDF]

Curr Res Food Sci
Xiong M, Plambeck J, Esatbeyoglu T, Buchweitz M.   +3 more
europepmc   +1 more source